Question

Biochem: please label the following biochemical pathways with the name of each compound, the enzyme involved in each reaction, the byproducts of each reaction if there are any (ATP, ADP, NADH, NADPH, FADH₂, CO₂, H₂O etc.)

FADH, NAD FAD COA NADH, H COA COA H 1 2 3 H 4 18 NH P-ribose COA çoo HNICH COA CH, Coo HC 11 10 +H2O 5 coon CH COO- HC "OOC OH сн. CH 14 coo COO NADH + H 6 9 15 HES Coo NAD" ÇOO- 17 CEO нсон C00 Pribose HC -OOCH HO CH CH Co сн. Coo Coo 8 7 ÇoO-* COAS COO CH, 13 "OOC 12 H COA CH2 CH HC coor сн. COO H C00 16 NH 0 Co P-ribose сн.

Answer 1

substrate enzyme product

1. Fatty acyl-CoA ---(Acyl-CoA dehydrogenase)--->  $\alpha \beta$enoyl- CoA

2.$\alpha \beta$enoyl- CoA ---( Enoyl-CoA hydratase)---> 3-hydroxy acyl -CoA

3.  3-hydroxy acyl -CoA ---(Hydroxyacyl-CoA dehydrogenase)---> $\beta$ -ketoacyl-CoA

4. $\beta$ -ketoacyl-CoA ---(CoA , thiolase) ----> acetyl CoA

5.acetyl CoA+ oxaloacetate ---(citrate synthase) ---> citrate

6. citrate ---( Aconitase) ---> isocitrate

7. isocitrate ---( isocitrate lyase ) ---> glyoxylate + succinate

8. glyoxylate ---( malalte synthase) ---> malate

9. malate ---( malate dehydrogenase) ---> oxaloacetate

10. oxaloacetate ---( aspartate aminotransferase ) ---> aspartate

11. IMP + aspartate+ GTP ---( Adenylosuccinate synthetase ) ---> adenylosuccinate + GDP

12. adenylosuccinate ---( Adenylosuccinate ) ---> AMP + fumerate

13. fumerate + H2O ---( fumerase ) ---> malate

14. citrate --- ( ATP citrate lyase ) --- > oxaloacetate

15. oxaloacetate + NADH/H+ -------> malate

16.malate --- ( NADP dependent malic enzyme) ----> pyuvate

17. succinyl- CoA + GDP +Pi ---( succinyl-CoA synthetase ) ---> succinate+ GTP