Question

Hardy-Weinberg Practice Problems: You need to list equations used and provide steps of problem solving. Providing answer itself is not enough for full grade. 1. You have sampled a population in which you know that the percentage of the homozygous recessive genotype (aa) is 36%. Calculate the frequency of the heterozygous genotype, homozygous dominant genotype and homozygous recessive genotype. 2. You have sampled a population in which you know that the percentage of the homozygous recessive genotype (aa) is 49%. What is the frequency of the recessive allele, and the frequency of the dominant allele? What is the frequency of heterozygous genotype? 3. Within a population of butterflies, the color brown allele (B) is dominant over the color white allele (b). And, 16% of all butterflies are white. Given this simple information, calculate the percentage of butterflies in the population that are heterozygous, and the frequency of homozygous dominant individuals. 4. Sickle-cell anemia is a genetic disease. At least one copy of dominant allele (s) exists in normal individuals. Individuals homozygous for the recessive allele (ss) have sickle shape red blood cells and often die due to collapsing red blood cells. In 2016, you studied Durban population (30,000 in total) in Africa. 270 individuals in the Durban population were born with severe sickle-cell

Answer 1

Answer:

1).

Homozygous recessive genotype frequency=aa= 30%=0.3

Frequency of recessive allele= a = sqrt of 0.3= 0.55

Frequency of dominant allele=A= 1- 0.55=0.45

Frequency of heterozygote =Aa= 2*0.45*0.55= 0.495

Frequency of Homozygous dominant genotype= AA= 0.45*0.45= 0.2025

Frequency of Homozygous recessive genotype = aa= 0.55*0.55= 0.3025

2).

Fr (aa)= 49%=0.49

Frequency of recessive allele= a= sqrt of 0.49= 0.7

Frequency of dominant allele=A= 1- 0.7= 0.3

Frequency of heterozygote=Aa= 2*0.7*0.3= 0.42

3).

Frequency of white= bb = 16%=0.16

Frequency of white allele = b= sqrt of 0.16= 0.4

Frequency of dominant allele= B= 1- 0.4= 0.6

Frequency of heterozygote= Bb = 2*0.6*0.4= 0.48

Frequency of Homozygous dominant= BB= 0.6*0.6=0.36

4).