Regulation of gene expression in eukaryotes are more difficult than that of the bacteria.Initially gene expression is regulated at the level of transcription. Transcription factors are proteins that play a role in regulating the transcription of genes by binding to specific regulatory nucleotide sequences.This is the most economical method of regulation. It is possible to control gene expression even after transcription. It includes regulating the processing of RNA molecules, including alternative splicing to produce more than one protein product from a single gene,capping and poly A tail addition, regulating the stability of mRNA molecules and by regulating the rate of translation. Translation can be regulated globally (for every mRNA in the cell) through changes in the availability or activity of the “helper” proteins. Helper proteins are the proteins which help in the correct positioning of ribosomes at the beginning of translation. The produced proteins also can be regulated by adding some chemical modification or bu removing amino acids.
Discuss all the different ways and mechanisms that eukaryotes use to regulate gene expression.
In eukaryotic cells, there are specific transcription factors (activators) that regulate gene expression. Describe the organization of eukaryotic genes (i.e. promoters/enhancers) and how transcription factors are able to control gene expression and enzyme activity. a) Throughout the course we discussed the enzyme lactase and how it is differently regulated (and therefore expressed) in different human populations. Describe how this gene is differently expressed in different populations and when this/these change(s) are predicted to have taken place. b) Differential gene expression...
Both prokaryotes and eukaryotes regulate gene expression, turning genes on and off in response to various cues. Which of the following mechanisms is common to both types of cells? Choose all that apply. alternative splicing of mRNA opening or condensing chromatin transcriptional regulation post-translational regulation
Each answer box represents a mechanism by which eukaryotes can regulate gene expression. Determine which of the five mechanisms each example represents. Not all examples will be used.
There are 5 types of RNAs. Which type is used to regulate gene expression by binding to complementary mRNAs to block gene expression or cause their degradation? rRNA mRNA miRNA tRNA
What is transcript factor? How does transcript factor regulate gene expression?
What is transcript factor. How does transcript factor regulate gene expression
5. How is RNA interference (RNAI) used to regulate gene expression in eukaryotes? 5 pts
5. How is RNA interference (RNAI) used to regulate gene expression in eukaryotes? 5 pts
Which of the following mechanisms to regulate gene expression are observed in eukaryotes, but are not generally observed in prokaryotes? Choose all that apply. Genes are grouped into operons, which allows transcriptional regulation to turn them all on together. RNA silencing selectively targets mRNA and destroys it to prevent further translation. Proteins can be activated or deactivated as a form of post-translational regulation. Epigenetic regulation can open or condense sectiosn of a chromosome, regulating which genes are transcribed. Regulatory proteins...