CHROMIC ACID OXIDATION Pre Lab Questions the amounts of materials that will be used from the...
Pre-lab Questions: Importance A one-step preparation of aspirin from its precursor, salicylic acid, via an ester formation illustrates one of synthetic organic chemistry's most important uses, making the drugs that treat all types of illnesses. OH HOOH Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the ancient Greeks as a treatment for pain...
QUESTIONS 1. What is the purpose of the sulfuric acid (yes, it's a catalyst, but why is it a catalyst? What is it doing that makes the reaction possible? Would the reaction just go slower without it, or would the reaction not go at all? Why?) 2. If isobutyl alcohol (2 methyl propanol) is used instead of tert butyl alcohol, a mixture of products is obtained. One the products is the same as the product obtained with the tert butyl...
I understand that equivalents is the ratio of the # of moles of a reactant or reagent compared to the # of moles of the substrate. But I am confused on how to answer this question and why the procedure would call for more NaI than Vanillin if Vanillin is the substance needed substituted. Can you help? Thanks! 3. How many equivalents of sodium iodide are used in this experiment? Show your calculation Speculate about why the procedure calls for...
Prelab questions 1,2, and 3 and Part E questions Also, write a flowchart of the experiments process in each part. EXPERIMENT 3 DETERMINATION OF Δo The d orbitals of a metal ion in an octahedral ligand or crystal field are split into a higher energyset (eg) and a lower energy set (t2g) as shown in the following energy level diagram. 11 The energy difference between the upper and lower energy levels is Δo, the octahedral crystal field splitting. The degree...
3-5 pls Post-Laboratory Questions-EXP 3 Nitration of Aromatic Compounds Name: Due after completing the lab. 1. Why is concentrated sulfuric acid employed in this reaction? What is the electrophile that is produced by the reaction of sulfuric acid and nitric acid? 2. Why is it important to maintain the reaction temperature low and the addition of nitric acid-sulfuric acid mixture carried out slowly? 3. Explain why concentrated H2SO, not concentrated HCl, was used in this experiment? 4. Which ring of...
What is the limiting reagent in this experiment? Acetophenone or aqueous bleach? 1. Add about 1.0 g (measured accurately) of acetophenone to 40 mL of the bleach solution (5% NaCl in water - this reactant should be included in your table of reagents!) in a 100 mL round bottom flask equipped with a magnetic stirrer. Clamp the flask in the fume hood above a stir plate. 2. After the initial reaction has subsided, boil the reaction mixture gently for 5...
numbers 1-3 Post-Laboratory Questions-EXP 3 Nitration of Aromatic Compounds Name: Due after completing the lab. 1. Why is concentrated sulfuric acid emploved in thie on? What is the electrophile that is produced by the reaction of sulfuric acid and nitric acid? 2. Why is it important to maintain the reaction temperature low and the addition of nitric acid-sulfuric acid mixture carried out slowly? 3. Explain why concentrated H2SO4, not concentrated HC1, was used in this experiment? 4. Which ring of...
Calculate the quantity (mmol) of reagents to be used in the assigned experiment. Which reagent is the limiting reagent? Show by calculations. 8. n the reaction of vanillin with silver oxide, what gets oxidized and what gets reduced? Part B: Miniscale Hydrolysis of Methyl Salicylate To a 25-mL round-bottom flask containing a spin bar, add 7.5 mL of 5 M NaOH and 1.0mL. of methyl salicylate. Swirl to mix. A white solid will form, which will eventually disap- pear as...
PROCEDURE CAUTION!!! Nitric acid and sulfuric acid are strong and corrosive acids. For that reason, avoid inhaling its vapors or causing any contact with the skin or clothing. Wear your protective glasses at all times. Use the extractors to work with these acids. A. Nitration of methyl benzoate 1. Preparation of the reactants. In the extractor you will find a burette with concentrated sulfuric acid, a second burette with concentrated nitric acid, clearly identified. Familiarize yourself with the scales of...
What is the mechanism (with curved arrows) for this reaction? 1. Add about 1.0 g (measured accurately) of acetophenone to 40 mL of the bleach solution (5% NaCl in water - this reactant should be included in your table of reagents!) in a 100 mL round bottom flask equipped with a magnetic stirrer. Clamp the flask in the fume hood above a stir plate. 2. After the initial reaction has subsided, boil the reaction mixture gently for 5 - 10...