In humans, sickle-cell anemia is caused by a recessive lethal allele Hbs. A healthy allele is...
In humans, sickle-cell anemia is caused by a recessive lethal allele Hbs. A healthy allele is denoted by Hba. Following is a table that shows the three possible genotypes, with the associated phenotypes.
| Genotype | Phenotype |
| Hba Hba | Healthy (no sign of disease) |
| HbaHbs | Healthy (no sign of disease) |
| Hbs Hbs | Shows symptoms of sickle-cell anemia |
What is the probability of two heterozygous individuals giving birth to a child who has a sickle-cell allele, but shows a healthy phenotype? Enter in your answer as a decimal.
Homework Answers
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In humans, sickle-cell anemia is caused by a recessive lethal
allele Hbs. A healthy allele is...
Use the following information to answer the next two questions. Sickle cell anemia is a disease...
Use the following information to answer the next two questions. Sickle cell anemia is a disease that is caused by a mutation in the gene that produces haemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces haemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell...
Please answer genetics questions 9 and 10 The following is the genetics of determination of blood...
Please answer genetics questions 9 and 10
The following is the genetics of determination of blood type in human. How many alleles are ever known that are involved in determination of blood type? How many alleles we as individual can we have in our DNA? Is this a typical example of monogenic trait? Digenic trait? Or trigenic trait? Is only one gene involved? Is A dominant over B allele? Is A dominant over O allele? Is B dominant over O...
In humans, sickle-cell anemia (HBBSHBBS) is caused by the recessive condition of an autosomal gene with...
In humans, sickle-cell anemia (HBBSHBBS) is caused by the recessive condition of an autosomal gene with two alleles: HBBA (wild-type) and HBBS (sickle-cell mutation). In one population, the frequency of individuals who do not suffer from sickle-cell anemia (HBBAHBBA and HBBAHBBS) is 0.9964. Assuming the population is in Hardy-Weinberg equilibrium, what is the frequency of the HBBS allele?
2. Hardy-Weinberg Equilibrium; chi-square test Sickle cell anemia is a recessive disorder caused by a recessive...
2. Hardy-Weinberg Equilibrium; chi-square test Sickle cell anemia is a recessive disorder caused by a recessive mutation (S) in the b-hemoglobin gene. 80% of affected SS individuals die before reproducing. Heterozygotes (AS) and homozygous dominant (AA) individuals do not have sickle cell anemia. The table below shows the number of people of each genotype in a population of 100 people in population of Cameroon. Observed # individuals in a Cameroon population AA AS SS 62 32 6 What are the...
6. Sickle cell anemia (disease) is described as an autosomal recessive condition (individuals must have two...
6. Sickle cell anemia (disease) is described as an autosomal recessive condition (individuals must have two copies of the recessive allele to display “sickle cell disease”). However, sickle cell trait (the heterozygous condition) has a unique phenotype. a. How would you classify/describe sickle cell trait at the organismal level (complete, incomplete, or co-dominance)? Explain your reasoning. b. How would you classify/describe sickle cell trait at the molecular level (complete, incomplete, or co-dominance)? Explain your reasoning. (HINT: think about the hemoglobin...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
(3) Sickle cell disease in humans is a blood disorder caused by a recessive alleles). If...
(3) Sickle cell disease in humans is a blood disorder caused by a recessive alleles). If two heterorous Individuals have a child, what are the chances the child will have sickle cell disease? (1 point) (4) Colorblindness is a recessive sexe linked tralt in humans. Rob (male) is colorblind; his wife Julle is not colorblind and is not a carrier Their daughter Susan and her husband Mike are expecting a baby. Mile is not colorblind. (5 points) • (a) List...
explain, in detail, the relationship between malaria and sickle-cell anemia. Why is having one sickle-cell allele...
explain, in detail, the relationship between malaria and sickle-cell anemia. Why is having one sickle-cell allele considered a selective advantage? Is this equally beneficial for someone who is homozygous recessive for sickle-cell? Why or why not? Note: use specific vocabulary to describe your answers (genotype, homozygous d, homozygous r, natural selection, heterozygous, etc)
Table 2. Results of blood and hemoglobin tests for case study. Subject Blood type (phenotype) Hemoglobin...
Table 2. Results of blood and hemoglobin tests for case
study.
Subject
Blood type (phenotype)
Hemoglobin genotype
Mother
A+
HbAS
Baby
A+
HbAA
Male Subject
O-
HbAS
Based on your results shown in Table 2, can you exclude the
possibility of paternity? Cite the specific results
that allow you to make this claim
What are ALL of the potential genotypes for each subject based
on blood type?
Define the difference between genotype and phenotype.
Supplementary Information A gene is a...
Sickle-cell anaemia is an example of how fitness depends on environmental conditions. In places where malaria,...
Sickle-cell anaemia is an example of how fitness depends on environmental conditions. In places where malaria, caused by Plasmodium falciparum is common, HbAHbS heterozygotes have a selective advantage compared to individuals who are homozygotes for the wild type allele. However, HbSHbS homozygotes suffer from sickle-cell anaemia and usually die before producing offspring. The relative fitness (w) of the three genotypes in Nigeria are: HbAHbA 0.78, HbAHbS 1.0 HbSHbS 0.07 a. What is the mathematical relationship between relative fitness and selection...
Please answer genetics questions 9 and 10
The following is the genetics of determination of blood type in human. How many alleles are ever known that are involved in determination of blood type? How many alleles we as individual can we have in our DNA? Is this a typical example of monogenic trait? Digenic trait? Or trigenic trait? Is only one gene involved? Is A dominant over B allele? Is A dominant over O allele? Is B dominant over O...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
(3) Sickle cell disease in humans is a blood disorder caused by a recessive alleles). If two heterorous Individuals have a child, what are the chances the child will have sickle cell disease? (1 point) (4) Colorblindness is a recessive sexe linked tralt in humans. Rob (male) is colorblind; his wife Julle is not colorblind and is not a carrier Their daughter Susan and her husband Mike are expecting a baby. Mile is not colorblind. (5 points) • (a) List...
Table 2. Results of blood and hemoglobin tests for case
study.
Subject
Blood type (phenotype)
Hemoglobin genotype
Mother
A+
HbAS
Baby
A+
HbAA
Male Subject
O-
HbAS
Based on your results shown in Table 2, can you exclude the
possibility of paternity? Cite the specific results
that allow you to make this claim
What are ALL of the potential genotypes for each subject based
on blood type?
Define the difference between genotype and phenotype.
Supplementary Information A gene is a...
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