In humans, sickle-cell anemia (HBBSHBBS) is caused by the recessive condition of an autosomal gene with...
In humans, sickle-cell anemia (HBBSHBBS) is caused by the recessive condition of an autosomal gene with two alleles: HBBA (wild-type) and HBBS (sickle-cell mutation). In one population, the frequency of individuals who do not suffer from sickle-cell anemia (HBBAHBBA and HBBAHBBS) is 0.9964. Assuming the population is in Hardy-Weinberg equilibrium, what is the frequency of the HBBS allele?
Homework Answers
p(HBBA)=a
p(HBBS)=b
p(HBBAHBBA)=a2
p(HBBSHBBS)=b2
p(HBBAHBBS)=2ab
Accordin to Hardy-weinberg principle
a2 +2ab+b2=1
so, b2=1-.9964
b=p(HBBS)=0.06
Add Answer to:
In humans, sickle-cell anemia (HBBSHBBS)
is caused by the recessive condition of an autosomal gene with...
2. Hardy-Weinberg Equilibrium; chi-square test Sickle cell anemia is a recessive disorder caused by a recessive...
2. Hardy-Weinberg Equilibrium; chi-square test Sickle cell anemia is a recessive disorder caused by a recessive mutation (S) in the b-hemoglobin gene. 80% of affected SS individuals die before reproducing. Heterozygotes (AS) and homozygous dominant (AA) individuals do not have sickle cell anemia. The table below shows the number of people of each genotype in a population of 100 people in population of Cameroon. Observed # individuals in a Cameroon population AA AS SS 62 32 6 What are the...
Cystic fibrosis is an autosomal recessive disease caused by a mutation in a single gene with...
Cystic fibrosis is an autosomal recessive disease caused by a mutation in a single gene with two alleles. Suppose the frequency of cystic fibrosis in a population is 3%. Assuming the gene is in HW equilibrium, calculate the allele and genotype frequencies. If the population consists of 100 individuals, how many are carriers (but unaffected) for the cystic fibrosis allele?
In humans, sickle-cell anemia is caused by a recessive lethal allele Hbs. A healthy allele is...
In humans, sickle-cell anemia is caused by a recessive lethal allele Hbs. A healthy allele is denoted by Hba. Following is a table that shows the three possible genotypes, with the associated phenotypes. Genotype Phenotype Hba Hba Healthy (no sign of disease) HbaHbs Healthy (no sign of disease) Hbs Hbs Shows symptoms of sickle-cell anemia What is the probability of two heterozygous individuals giving birth to a child who has a sickle-cell allele, but shows a healthy phenotype? Enter in...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele,...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, though, in areas with a high rate of malaria, heterozygotes that carry the sickle cell allele have a higher fitness than do individuals that are...
Sickle-cell anemia is caused by a single point mutation in the hemoglobin of human red blood cells. It is a recessive gene. People who have sickle cell anemia are homozygous recessive and suffer terribly from this disorde
Sickle-cell anemia is caused by a single point mutation in the hemoglobin of human red blood cells. It is a recessive gene. People who have sickle cell anemia are homozygous recessive and suffer terribly from this disorder. Now I have stated in lecture that mutations are neither good nor bad. Rather it depends on how the mutation effects the survival of the species. If the mutation harms the survival of the species it is bad, if it helps the survival...
30) In Tanzania, 4% of the population are homozygous recessive for a condition called sickle cell...
30) In Tanzania, 4% of the population are homozygous recessive for a condition called sickle cell anemia. From this data, a) Calculate the frequency of the dominant and recessive alleles. 1-04-06 b) Calculate the genotype frequencies for individuals not carrying a sickle cell allele, carriers and individuals who have the disease.
6. Sickle cell anemia (disease) is described as an autosomal recessive condition (individuals must have two...
6. Sickle cell anemia (disease) is described as an autosomal recessive condition (individuals must have two copies of the recessive allele to display “sickle cell disease”). However, sickle cell trait (the heterozygous condition) has a unique phenotype. a. How would you classify/describe sickle cell trait at the organismal level (complete, incomplete, or co-dominance)? Explain your reasoning. b. How would you classify/describe sickle cell trait at the molecular level (complete, incomplete, or co-dominance)? Explain your reasoning. (HINT: think about the hemoglobin...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele,...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, in areas with high rates of malaria, a single Sallele confers some resistance to malarial infection. Suppose there is a population with the observed and...
In a hypothetical population which is in Hardy Weinberg equilibrium, the frequency for a recessive allele...
In a hypothetical population which is in Hardy Weinberg equilibrium, the frequency for a recessive allele is 30%. What percentage of the population would be expected to show the dominant trait in the next generation? Humans who are born homozygous for the recessive sickle cell allele die of sickle cell anemia, while those who are heterozygous are resistant to malaria (see chapter 4 for more information on this balanced polymorphism). 4% of the population of the Congo are homozygous recessive for...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, though, in areas with a high rate of malaria, heterozygotes that carry the sickle cell allele have a higher fitness than do individuals that are...
30) In Tanzania, 4% of the population are homozygous recessive for a condition called sickle cell anemia. From this data, a) Calculate the frequency of the dominant and recessive alleles. 1-04-06 b) Calculate the genotype frequencies for individuals not carrying a sickle cell allele, carriers and individuals who have the disease.
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, in areas with high rates of malaria, a single Sallele confers some resistance to malarial infection. Suppose there is a population with the observed and...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
Most questions answered within 3 hours.
-
U.S. health spending per capita in 2012 was
less than $3,000.
between $3,000 and $5,000.
between...
asked 46 minutes ago -
A platform rotating at 6.0 rad/sec slows down with constant
angular acceleration and stops after 25s,...
asked 1 hour ago -
Consider a two-sided Z interval for population mean ?. How will
the length of the confidence...
asked 5 hours ago -
Topic: Poverty and its solution
1. Introduction (50 words)
2. Causes of Poverty (150 words)
3....
asked 6 hours ago -
Leaky Pipe, a local retailer of plumbing supplies, faces
demand for one of its SKUs at...
asked 6 hours ago -
Assign costs -- In August , Jay Corp determined its cost per
equivalent units in department...
asked 7 hours ago -
A photon is emitted when a hydrogen atom undergoes a transition
from the n = 8...
asked 8 hours ago -
A metal wire of diameter 1.00 mm can support a tension of 0.250
kN. A construction...
asked 8 hours ago -
If 5.0 Liters of a gas is allowed to expand against a pressure
of 1.10 atm...
asked 8 hours ago -
Are the
actions undertaken by the companies or individuals in the following
scenarios legal or illegal...
asked 9 hours ago -
A quantum mechanical transition between two rotational energy
levels is measured between E0 = 3.6x10-23 J...
asked 9 hours ago -
Inside a radiation therapy device, an electron is in the
presence of a uniform electric field...
asked 10 hours ago