Notes: A ‘detailed’ mechanism should illustrate all intermediates, by-products, and electron-pushing arrows. The marking scheme is given for each question as a guide; It is subject to minor changes.
In class, we learned how to synthesize epoxides from alkenes using meta-chloroperbenzoic acid (mCPBA). Epoxides, like bromonium ions and mercuronium ions, can be ring-opened with various nucleophiles. The stereochemistry of the product depends on if the ring-opening occurs under acidic or basic conditions. The following two reactions – ring opening of an epoxide with water – illustrate this effect. Explain why the outcome of the reaction changes under these two conditions and provide electron-pushing arrows to explain the mechanisms. The following websites may be useful:
https://www.masterorganicchemistry.com/2015/02/10/opening-of-epoxide-with-base/
https://www.masterorganicchemistry.com/2015/02/02/opening-of-epoxides-with-acid/
Notes: A ‘detailed’ mechanism should illustrate all intermediates, by-products, and electron-pushing arrows. The marking scheme is...
Notes: A ‘detailed’ mechanism should illustrate all intermediates, by-products, and electron-pushing arrows. The marking scheme is given for each question as a guide; It is subject to minor changes. In class, we learned how to sulfonate aromatic rings by treating them with SO3 and H2SO4. This reaction is reversible. Propose a detailed mechanism for this reverse reaction. Note, catalysts are reactants that are regenerated at the end of a reaction sequence.
1. (10 marks the wol 1. (10 marks) The Wolff-Kishner reduction is a method to transform ketones into alkanes. An example is provided below. step 1 step 2 NH oh oh oh oon HẠN-NH, KOH/H20 A mechanism for the Wolff-Kishner reduction is proposed online at the following website: However, all steps and all electron-pushing arrows are not clearly illustrated in this mechanism. Propose a detailed mechanism with all electron-pushing arrows for both steps of the Wolff-Kishner reduction. Notice the first...
Epoxides, like bromonium ions and mercuronium ions, can be ring-opened with various nucleophiles. The stereochemistry of the product depends on if the ring-opening occurs under acidic or basic conditions. The following two reactions – ring opening of an epoxide with water – illustrate this effect. Explain why the outcome of the reaction changes under these two conditions and provide electron-pushing arrows to explain the mechanisms. PHOLD H30*/H20 PHOI OH | PhD NaOH,H,O HO D
please draw the full mechanism with all electron pushing arrows, reactant structures, intermediates, and products for the hydroboration oxidation reaction using 1-octene to prepare 1-octanol.