Draw the structures of the following two oligopeptides with their cysteine residues cross-linked by a disulfide bond: Val-Cys, Thr-Cys-Pro
Draw the structures of the following two oligopeptides with their cysteine residues cross-linked by a disulfide...
Tissue factor (TF) contains four cysteine residues that form two disulfide bonds in the native structure of TF. Suppose TF is reduced and unfolded in urea. If the reduced unfolded protein were oxidized prior to the removal of the urea, what fraction of the resulting mixture would you expect to possess native disulfide bonds? Express your answer using three significant figures.
Indicate which of the amino acid residues in the following peptide sequence contains a group that has a negative charge for its most likely charge state at pH 10. Phe-Val-Pro-His-Trp-Asn-Cys-Thr-Asp Please explain in detail how you got the answer. thank you!
I 79) The sequence of a nonapeptide was determined from the following evidence: a. A peptide is acyclic compound containing a disulfide bridge between two cysteine residues. b. When the disulfide bridge is reduced, peptide has the constitution Asn, Cys2, Gin, Gly, Ile, Leu, Pro, Tyr. Partial hydrolysis of reduced peptide yields seven fragments: Asp-Cys, Ile-Glu, Cys-Tyr, Leu-Gly, Tyr-Ile-Glu, Glu-Asp-Cys, and Cys-Pro-Leu. d. Gly is the C-terminal group. C W What is the amino acid sequence of reduced peptide? What...
NAME 2a) Lanthionne is a dimeric amino acid with the chemical formula HOOC-CH NH CH SCH-CHINH COOH),- Lanthionine is composed of two alanine residues that are cross-linked on their ß-carbon atoms by a thioether linkage. It can be synthesized by the Michael addition of cysteine to dehydroalanine (DHA, 2-aminoprop-2-enoic acid). ILLUSTRATE this Michael addition and its mechanism NAME 2a) Lanthionne is a dimeric amino acid with the chemical formula HOOC-CH NH CH SCH-CHINH COOH),- Lanthionine is composed of two alanine...
Vasopressin, a nonapeptide hormone secreted by the pituitary gland, functions by stimulating the kidney to retain water. Its sequence was determined by the following evidence: 1. Vasopressin is a cyclic compound containing a disulfide bridge between two cysteine residues. 2. When the disulfide bridge is reduced, vasopressin has the constitution Arg, Asn, Cys2, Gln, Gly, Ile, Phe, Pro. 3. Partial hydrolysis of vasopressin yields seven fragments: Asp-Cys, Ile-Glu, Cys-Phe, Arg-Gly, Phe-Ile-Glu, Glu-Asp-Cys, Cys-Pro-Arg. 4. Gly is the C-terminal group. 5....
Based on the chemical properties of the residues, which of the following sequences could form the following? At least one should be placed in each category. Based on the chemical properties of the residues, which of the following sequences could form the following? At least one should be placed in each category Most likely an amphipathic Most likely an amphipathic B sheet a helix Most likely a turn/ loop Not amphipathic Asn-Leu-Ala-Asp-Ser-Phe-Arg-Gin-lle Lys-Ser-Thr-Asn-Glu-Gin-Asn-Ser-Arg Gin-lle-Thr-Phe-Thr-Leu-GIn-Val-Ser Lys-GIn-Asn-Glu-Pro-Arg-Ala-Asn-Glu Arg-Phe-GIn-lle-His-Val-Gin-Phe-Glu Ala-Phe-Leu-Val-lle-Trp-Phe-Val-Ala
Vasopressin, a nonapeptide hormone secreted by the pituitary gland, functions by stimulating the kidney to retain water. Its sequence was determined by the following evidence: 1. Vasopressin is a cyclic compound containing a disulfide bridge between two cysteine residues. 2. When the disulfide bridge is reduced, vasopressin has the constitution Arg, Asn, Cys2, Gln, Gly, Ile, Phe, Pro. 3. Partial hydrolysis of vasopressin yields seven fragments: Asp-Cys, Ile-Glu, Cys-Phe, Arg-Gly, Phe-Ile-Glu, Glu-Asp-Cys, Cys-Pro-Arg. 4. Gly is the C-terminal group. 5....
PLEASE HELP OCHEM QUESTION 1. In the following protein, identify the type of bonding or interaction that is responsible for holding the two peptide chains together at each amino acid pair, above (A) and below (B). Gly - Ala - Ser - Cys - Val - Asp - Leu - Thr - His - Ile-Tyr-Glu - Phe - Lys - Cys - Met - Asn Val - Leu -Gin-Cys - Pro-Lys - Met - Tyr - Asp -Phe-Asn-Lys - Ile...
B. DIPEPTIDES Draw the two dipeptides which can be formed from serine and cysteine. Circle the amide bonds. Hint: It helps to draw the amino group to the left and carboxyl to the right when orienting the amino acids. Ser-Cys Cys-Ser
Tertiary structure is maintained by Select one: o peptide bond o hydrogen bond o disulphide bond o all of the above Myoglobin binding of oxygen depends on: Select one: O a. the oxygen concentration O b. the haemoglobin concentration O c. the affinity of myoglobin for the oxygen d. a) and c) e. a), b) and c) Amino acid residues commonly found in B-turns are: Select one: o alanine (Ala) and glycine (Gly). O two cysteine (Cys) residues. o proline...