McCardle syndrome is due to a skeletal muscle deficiency of glycogen phosphorylase. Which of the following...
McCardle syndrome is due to a skeletal muscle deficiency of
glycogen phosphorylase. Which of the following would be observed in
such a patient with this syndrome?
Skeletal muscle has high level of glycogen with no branches
Fasting hypoglycemia
Skeletal muscle has high level of glycogen with shorter than normal
branches
Skeletal muscle has abnormally low glycogen
Skeletal muscle has high level of glycogen with normal
structure
Homework Answers
Solution:-
The correct answer for this question is "Skeletal muscle has high level of glycogen with normal structure". This disease is also named as Type v glycogen strorage disease. It is an autosomal recessive disorder which is marked by the deficiency of enzyme glycogen phosphorylase. This leads to the accumulation of glycogen.However, the structure of glycogen remains normal.
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McCardle syndrome is due to a skeletal muscle deficiency of
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3.
4.
5.
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Q5. The phosphorylase enzyme, which is involved in breakdown of glycogen to glucose, is controlled by both allosteric mechanisms and posttranslational modification. A) Describe how the T to R transition and activity of glycogen phosphorylase would change under the following conditions: i) high AMP levels and activation of phosphoprotein phosphatase, ii) activation of phosphorylase kinase, ili) activation of phosphorylase kinase and high glucose levels. B) What properties would an uncompetitive inhibitor of glycogen phosphorylase have, what would the Lineweaver Burk...
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1.
2.
3.
4.
5.
A patient presents with a deficiency of thiamine. If this patient's liver cells are compared with normal cells, which of the following products would be decreased in the thiamine-deficient cell (when compared to the normal cells) if the cells are only given glucose as a fuel? O Alanine O co2 Lactate O NADP+ e Pyruvate A patient is newly diagnosed with a deficiency in fructokinase. Which of the following will not be a metabolic consequence...
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night. Tests showed fasting hypoglycemia (low blood glucose
concentration), increased serum lipid levels, elevated blood
lactate after glucose administration, and elevated uric acid. The
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in hepatocytes. (Assume the glycogen is of normal structure.)
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Answer the question...
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