Question

33. Evidence suggests that _____ of ______ from nucleosomes in the wake of an elongating RNA polymerase prevents the inappropriate __________ within the internal coding region of a gene.

a) addition, acetyl groups, initiation of transcription

b) removal, acetyl groups, initiation of translation

c) removal, acetyl groups, initiation of transcription

d) removal, methyl groups, initiation of transcription

e) addition, methyl groups, initiation of translation

46. All of the following are qualities of the nuclear membrane EXCEPT

a) it is continuous with the RER membrane.       

b) it has openings called nuclear pore complexes

c) its fluid is referred to as nucleoplasm.             

d) the outer member is studded with ribosomes.

e) its interior is lined with cytoskeletal proteins called actin

50. All of the following are characteristics of the centromere EXCEPT

a) it contains a H3 histone variant called CENP-A         

b) it is composed of α–satellite DNA

c) it contains highly repetitive DNA sequences              

d) it is constitutive heterochromatin

e) it serves as the platform for the assembly of the kinetochore.

Answer 1

Evidence suggests that removal of acetyl groups from nucleosomes in the wake of an elongating RNA polymerase prevents the inappropriate initiation of transcription within the internal coding region of a gene.

H3K36 methylation is enhanced by an enzyme that moves with the elongating RNA polymerase. When the methylation of residue is complete, it functions as an enlisting site for other enzyme that enhances the removal of the acetyl groups from the residues (lysine) in transcribed part of gene.

hope the answer helps.