Problem

Read the blood coagulation solved problem on the CD-ROM/Web. Load the blood coagulation Li...

Read the blood coagulation solved problem on the CD-ROM/Web. Load the blood coagulation Living Example Problem from the CD-ROM. Use part (b) for the complete set of coagulation equations. First verify that you can obtain the curve shown in the shaded Side note on page 325.

(a) Plot some of the other species concentrations as a function of time, specifically TFVIIa, TFVIIaX, TFVIIaXa, and TFVIIaIX. Do you notice anything unusual about these concentration -time curves, such as two maxima?

(b) How does the full solution compare with the solution for the abbreviated reactions? What reactions can you eliminate and still get a reasonable approximation to the thrombin-time curve?

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Solutions For Problems in Chapter 6