Question

Draw the major product formed when the following epoxide reacts with methanol in the presence of sulfuric acid. Use w...

Draw the major product formed when the following e

Draw the major product formed when the following epoxide reacts with methanol in the presence of sulfuric acid. Use wedge/dash bonds, including H\'s at each stereogenic center, to show the stereochemistry of the product.

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Answer #1
Concepts and reason

The concept is to draw the major organic product of a reaction between oxirane and methanol in presence of an acid.

Fundamentals

Methanol acts as a nucleophile, and sulfuric acid acts as a catalyst.

In step-1, sulfuric acid protonates the oxirane oxygen, followed by nucleophilic attack at more substituted carbon takes place.

H2SO4
WWW
HC-
Ink
H3C-
(2S,3S)-2-ethyl-2,3-dimethyloxirane

The reaction is,

НАСНЫС
CH3OH
ди. 

НС
H3CO
(25,3R)-3-methoxy-3-methylpentan-2-ol

Ans:

Thus, the major organic product is,

HC,
H,C
H/
CHỊ
H3CO

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