10) Show how to synthesize 4-Phenyl-2-butanone using the Acetoacetic Ester Synthesis. Start with Ethyl 3-oxobutanoate (C6H1003).
6. Using either malonic ester synthesis or acetoacetic ester synthesis, outline a reaction scheme in each case to show how you will synthesize compounds A and B below. [Show all steps with structure of all intermediates and necessary reagents). A. 3-butyl-2-tetradecanone B. 2-propylpentadecanoic acid
11) Show how to synthesize 2-Methylhexanoic acid using the Malonic Ester Synthesis. Start with Diethyl propanedioate (C7H1204)
A chemist wanted to synthesize the following compound using the acetoacetic acid ester synthesis. Two alkyl bromides will be needed for the reaction. Draw the structure of the two required alkyl bromides. Don't draw anything else, just the two alkyl bromides. Насло مکم CH2 alkyl bromide 1 alkyl bromide 2
In order to synthesize 5-methyl-2-hexanone via acetoacetic ester synthesis, which of the following compounds should be reacted with the enolate ion generated by the reaction of ethylacetoacetate with sodium ethoxide? A) 2-methylpropanal B) isobutyl bromide C) 1-bromo-3-methylbutane D) 2-methyl-1-propanol E) none of the above Correct answer is B. Please explain why
Using curved arrows, show the mechanism of preparing 2-ethyl-3- methylbutanoic acid via the Malonic Ester Synthesis route.
please show all steps and explanation 3 3. (a) Using an acetoacetic ester of your choice and any other needed reagents/reactants, propose the synthesis of:a yheol bebivong elehetem nheta erll onieu A bnuoqmao to 2i2stne MI ( beiupe1 ton e16 2m2insrdoemnoitbs99 ( ) 3,6-Dimethyl-2-heptanone. (i) 2,5-Hexanediol (b) Using a dialkyl malonate of your choice propose an efficient synthesis of: () 2-Benzyl-1,5-pentanedioic acid. (i) 4-Methyl-1-pentanol
QUESTION 1 Synthesize 3-methyl-1-phenyl-1-butanone from benzoic acid using a Claisen condensation Attach File Browse My Computer Browse Content Collection QUESTION 2 What is the product of ethyl benzoate and ethyl-2-phenylacetate with NaOEU/EtOH followed by acid workup? Attach File Browse My Computer Browse Content Collection QUESTION 3 "Using an enamine, convert acetophenone to 1-phenylbutane-1,3-dione" Attach File Browse My Computer Browse Content Collection QUESTION 4 What's the best base to use for this reaction? NOTE: Reagents are missing. CO2Et EtOK MeOK
9. Show two pathways to synthesize cyclopentyl ethyl ether using the Williamson ether synthesis. Which one is preferred and why? (4 pts)
5. How might you use acetoacetic ester to perform the following synthesis. (10 points). 3 om s nsonbyH o nap9byi 6. Use any reagents you wish to perform the following transformation. Hint: the first step is a chem 242L experiment.(10 points) ot stohosa y uoy dr woH 7. How would you perform the following syntheses using eneamines and any chloro compound you want to use. (8 points). olen eta se s au uoy ialin wolt.
Question 5 0.5 pts ethyl 2-isopropyl-3-oxobutanoate + NaOEt +EtOH + methyl iodide --> something else! no reaction! ethyl 3-oxo-2 buteneoate ethyl 2-propyl-2-methyl-3-oxobutanoate ethyl 2-isopropyl-2-methyl-3-oxobutanoate Question 6 0.5 pts sat ethyl 2-isopropyl-2-methyl-3-oxobutanoate + KOH/water then dilute sulfuric acid and heat --> something else! ethyl 2-isopropyl-2-methyl-3-oxobutanoic acid 3,4-dimethyl-2-pentanone 2,3-dimethyl-4-pentanone 3,3-dimethyl-2-pentanone