Question

Elimination pathways compete with substitution pathways and a minor products is usually obtained. What is the best way to favor elimination over substitution

Answer 1

- Q. Elemination pathways Compete with substitution pathways and a minor products is usually obtained, what is the best way to favous elemination over substitution - # Ano p a Elimination versus substitution ③ Nucleophiles that are strong bases favour elemination over aubstitution famous ® Nucleophiles (or bases) that are bulky elimination over substitution. ③ High temperature favour elemination over substitution # Discussion : favour elemination ③ Nucleophiles that are strong bases over substitution. EtOH behaves as weak base where as Na det behaves as strong base so it gives elemination es Strong base abstract proton rather attacking on carbon centre. DEL NA ETH Etoh means - CH-CH2-OH

① Nucleophiles (or bases) that are burney over Substitution. favour elemination To attack the carbon nucleophile have to pass through the other substituents of that carbon. So larger nucleophile (or base) does not favou this steric kinderence - rather rather it it abstract abst Smaller size proton and give elemination product. ㅄ en wBy Wor SNB I KOH no WOH Substitution Telemination © High temperature favours elemination over Substitution In an elemination, two molecules become three. In Substitution two moleutes form two new molecules. So as is greater for elemination AG = VH – T4S So with increase in temperature All becomes more negative for elemination which is thermodynamically more favourable.