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28·The nurse understands that the route of drug administration that is the fastest acting among the routes presented is 1. Buccal 3. Subcutancous 4.
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ANS: A ( BUCCAL ROUTE)

Buccal administration of medication is a way of giving medicine orally or by mouth. It involves placement of the drug between the gums and cheek, where it also dissolves and is absorbed into the blood. The cheek area have many capillaries and tiny blood vessels. Therefore, the drugs can be absorbed directly into the bloodstream without going through the digestive system. Moreover, buccal formulations can provide extended-release options to provide long-lasting effects.

Intramuscular usually performed into the muscles. It also have larger and more blood vessels than subcutaneous tissues and injections have faster rates of absorption than subcutaneous or intradermal injections. But the drug absorption depends on the muscle blood flow. It is also possible to have slower effects of drug on patients. Most preferred method among Parenteral administration in intravenous.

Subcutaneous is performed under the skin (Insulin). It have low bioavailability and the rate of absorption depends on the different formulations of the drug( Eg., fast-acting versus slow acting insulin preparations)

Transdermal administration is a diffusion of medication through the intact skin for systemic rather than topical administration. For example; transdermal patches or nicotine patches used for the treatment of addiction. Absorption through this route is slow but have long-lasting effects on patients.

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