Question

Exercise 22-14 Explain the regioselectivity observed in the following reaction. (Hint: C the methoxy group on the selectivity of attack by amide ion on the intermedi the intermediate trapping The utility of onsiders rived from nitro ctrophil o philic aromi can picture the philic nitration OCH HON OCH KNH, liquid NHÀ -KB D(X) Major Mine OH

Answer 1

Sog eleminalibu pocees ta kas plare Fixxf B OCH3 acty NH2 KB Then Secendary addition takes place NH2 NHIO OCH3 NH2 .OCH2 I (Magor) NH2 OCH3 NH-H I (Minor) Explauedhoy repulsion Product T Obtained in mayor auouut beaaute Loue pairs af beluocen N aud o Qess thau producd