Predict the product of the following reaction sequence. 1.LDA THF,- 78°C
Provide the products for the following reactions: 1. LDA, THF, -78 C 1. LDA, THF, -78 C a yoyo a la misma 0 2. VI NaOCH3, CH3OH 1 eq. 2. H30*. H20
Draw the product of the following reaction sequence. Ho, 6 ܂ 1.LDA,THF
. Predict the principle organic product from the reaction below. 1. LDA, - 78 °C 2. Eti Predict the principle organic product from the reaction below. 1. NaOme 2. H30*
Predict the product of the following reaction sequence. NaH THF
Predict the products for each reaction shown below N NaOH N NaOH THF LDA 1) NaH, THF EtO THF-78 °C 2) CH3CH2Br heat HO CH3COOH KOH CH3NH2 KOH MeOH 1) NaOMe, MeOH 1) HCI, H20 OH 2) PhCH2Br 2) 180 °C
OH LDA - в THF, -78 °C (a) There are four possible sites of deprotonation on compound A. Re-draw compound A, indicating each of these sites with an asterisk. (2] (b) Under these conditions, deprotonation with LDA gives the kinetic lithium enolate B. Give a curly arrow mechanism for the formation of B. [2] (c) Draw a curly arrow mechanism for the intramolecular aldol reaction of enolate B to give product C. [3] (d) Draw a curly arrow mechanism for...
Complete the following reaction sequence. Complete the following reaction sequence ' 4 pts stucture iii. i i 1. LDA, -78 °C, THF 2. H30 1. LDA, -78 °C, THE heat 1.5 pts each step de : 1.5 pts each step
For the following sequence of reactions: 1. LDA (1.2 eq. -78 C) Final Major Organic Product? H 3. HO 4. heat a. Draw the final product (5 points) b. Draw a detailed, arrow pushing mechanism, for all the steps (for full credit, do not skip any steps). (9 pts)
1) Predict the major product for the following reaction. (LDA is a strong base) 1. LDA H 2. نم H LDA 3. H20
Provide the major product for the following reactions: b. NaH, THF CH Br 1.1 eq LDA, THF D O NaOD 1. LDA (1.1 eq) 2. CH2CH 3. LDA (1.1 eq, -78 °C) 4. CH 1 equiv. Br2 NaOH, H2O