based on the strength and the type of alkyl halide the product is as follows
1. Determine if E1 or E2 and the product formed. H₂O H2O t-butoxide DMSO OCH 3...
3. Determine if Sy1, S2, El or E2 and the product formed. Br CH,OH 1,0 c + CHCOOH ascol bus DMSO + CH,CH:09 acetone Br (CH),CO DME + 'OH acetronitrile X CH,OH 7,0
For each of the following reactions, determine which ELIMINATION mechanism (E1 or E2) will occur. Alkyl Halide Substitution: Methyl 1° 2° 3° Base Strength: Strong Weak Mechanism Type: E1 E2 Draw the mechanism that leads to ALL products for the reaction. Finally, underline the major product of the elimination reaction: H3C OH H2C H2C1 Br CHE
Regioselectivity of E1 and E2 Reactions 3. The reaction between a 1,2-dimethylcyclohexanol and concentrated strong acid results in an E1 reaction. Show the first step in this reaction (consider that the acid catalyst can protonate the OH group which eventually can form H2O that can act as a good leaving group). а. сн, OH conc.H2SO4 CH3 b. What is the geometry at the reaction center of the intermediate? Show the final step and all possible alkene products с. State the...
3. Determine the mechanism of nucleophilic substitution (SNI or SN2) for each reaction and draw the products. Be aware of stereochemistry. 8 + CN - dletone m et och cun, DE Br + OCH₂ CH₂ DME 4. Draw all constitutional isomers formed during each elimination reaction after determining whether it is E1 or E2. habel it as El or E2. госна. a y "ocha, B b. Tă CH₃OH Br -OH
please explain why and how they are E2/SN2/SN1/E1 3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SNI, S2, El, or E2). • NaOH H20 CH,CH ON CH,CH OH CH ON CH,OH CH OH Na DMSO
1. Determine whether the following reactions will go through SN1, SN2, E1, or E2 mechanism a. 1-bromobutane + sodium hydroxide b. 2-chloro-2-methylpentane + sodium hydroxide + heat C. 2,3-dimethyl-3-bromopentane + water d. 2-bromobutane + methanol 2. Draw the major product for the following reactions (draw both products if racemic): NaSH DMSO TsO CHA Nal CH, acetone CH,CH,ONa+ ethanol CH,OH/H-0 Solite Nal (1 equiv.) acetone F CH2CH OH 25°C
Reaction names such as SN1, SN2, E1, E2, acid-base, etc and major product? derstanding of Chemistry 231 Reactions (acid-base, functional group transformations, keywords, concepts, and reaction mechanisms) to... (1) correctly identify and label each in reaction by writing each reaction's name next to the reaction arrow (1 point each); and, (2) correctly draw the major product or products of each individual reaction (1 point each). HOAC HzCNH2 B(OCH3)3 HEC NH2 H₂cm NaOAC DMSO H3C NaOAC DMSO Me KOt-Bu . Ph...
Problem Set (SNZ, SN1, E2, E1) 1. Draw the product for the reactions below: B) B) [Xal CH.CH.CH но SNIE CHE 2. Draw the organic products formed in each reaction. OC(CH3) OCH.CH KOC(CH3)3 12 equiv) DMSO CH3CH2OH HO
determine whether the reaction is Sn1, Sn2, E1 or E2 & draw the major product Br Me TH NaOET Me H D Br EtOH Me Ph
4. Provide the products of each reaction (3pts, 2pts) 1. H2O+ OCH; 2. NaOCH, CHOH OCH 3. H, A 4. NaCN 1. LDA 2. Pho 3. H , A 4. EtMgBr 5. Provide an arrow-pushing mechanism for the reaction below, and state how many product stereoisomers are possible (5 pts) NO2 cat. KOH ЕКОН