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2. What is the dynamic range problem and how does it affect the efficiency of a...

2. What is the dynamic range problem and how does it affect the efficiency of a chromatographic analysis?
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Chromatography is a laboratory technique which is used for the separation of mixture of compounds. In chromatography dynamic range refers to the performance of the detector. Usually there are two dynamic ranges : (a) linear dynamic range and (b) dynamic range per second. The dynamic range can be explained as range of solute concentration over which the detector continues to respond to changes in solute concentration. It can extend from a minimum detectable concentration to that concentration where the output no longer increases with increase in solute concentration. Hence dynamic range problem can affect the efficiency of chromatography as explained above.

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