Question

2. Complete the El reaction and answer the following questions. Reagent: Major El product: AH>O a. Draw a mechanism of the reaction above. b. Draw an energy diagram of the reaction. Provide the structures of the starting material, intermediates product, and all transition states.

Answer 1

ANSWER

Concept of E1 Reaction is

• Non Stereospecific - follow Zaitsav(Syetseff) Rule

• Non-Concerted - has carbonation intermediate - favoured for tertiary Leaving group as well Secondary.

• Unimolecular - Rate only depends on the concentration of substrate.

• Does not occur with primary alkyl halides(leaving group)

• Strong acid can promote loss of OH as H2O and OR as HOR if tertiary and conjugate carbonation formed.

a) $Mechanism of E1 Reaction:-$ ​​​

Step1 :- Loss of Leaving group, which leaves in very slow step (RDS) resulting from a Carbonation.

Step2:- Base attacks a neighbouring hydrogen to Fast, forcing the electron from hydrogen-Carbon bond with some energy(∆H greater than Zero) to make the double bond.

step- ata -ce is leaving Aa Ros grown step-2 fast INC + Base (8) awé Major El Product cig - TSLIJA STS (2) ENERGY Ha City Intermectiate Reaction progress