Question

SN2 Laboratory Experiment Work-Sheet 1. Identify the compounds below with the title "nucleophile" or "electrophile", in terms of the lab reaction. NUORO plecrophie он O CIL OH 1.89 grams 2. How many grams of 4-chlorophenol are in the 10ml. of a 1 M sodium 4- chlorophenolate 2.5 M solution which you will use in lab? 3. How many grams of Sodium Hydroxide are in the 10nl of a 1 M sodium 4- 0.709 chlorophenolate 2.5 M solution which you will use in lab? 4. Define Reflux? 5. Why does the product precipitate out of solution when HC1 is added in step 6? 6. What is the theoretical yield of the reaction? 7. What was the experimental yield of the reaction? 8. What was the percent yield of the reaction? 9. Chloroacetic acid has two electrophilic carbons, below on the drawing indicate, by circling, the two electrophilic carbons. COH 10. Why does the nucleophilic attack take place at one electrophilic carbon but not the other? 11. Draw the complete reaction mechanism.

Answer 1

1) electron pair donor nucdeophile electrophile electron pair acceptor Nucleophile Electrophile OH OH Carbonyl carbon has partial +ve charge. It accepts electron pairs Hence, it s electrophile 3 double bonds in benezene ring are eectron rich They donate electron pairs Hence, it is nucleophile