Page 7 i. State which reaction in each of these pairs that you would expect to...
11.32 ▲ Which reaction in each of the following pairs would you expect to be faster? (a) The SN2 displacement by I- on CH3Cl or on CH3OTos (b) The SN2 displacement by CH3CO2 on bromoethane or or bromocyclohexane (c) The SN2 displacement on 2-bromopropane by CH3CH20- or by CN (d) The SN2 displacement by HC C- on bromomethane in benzene or in acetonitrile 11.33 Predict the product and give the stereochemistry resulting from reaction of each of the following nucleophiles...
Page 2 3. I State which reagent you would expect to be more nucleophilic. (1 pt.) ii. Explain why you would expect your choice to be more nucleophilic. (2 pts.) a) CH,CH,OH or CH,CH,0- b) Ph-S or Ph-0-
1. Arrange the following alkyl halide electrophiles with respect to Sn2 reactivity (least reactive → most reactive). Explain D-ci +ci ~ Α 2. Which compound in each of the following pairs will react faster in an SN2 reaction with HO-. Briefly provide your reasoning to support your answer a) CH3Br or CH31 b) CH3CH2l in ethanol or dimethyl sulfoxide c) (CH3)3CCI or CH3CI 3. Each of the following molecules contain two halogens of different kinds. In each case, determine which...
3. State which reagent you would expect to be more nucleophilic (1 pt.) ii. Explain why you would expect your choice to be more nucleophilic (2 pts.) a) CH CH.OH or CH CHO b) Ph-5 or Ph-O-
please explain how i know which is faster
I. (15 pts) A. (9 pts) In each of the following pairs, circle the compound, which reacts faster or has the larger (more favorable) equilibrium constant for the indicated reaction H. OCH20% CH3 H CH C cid-catalyzed hydrolysis H ocH2CH3 23 why?? equilibrium constant 3 CH3 r hydration 3 aceto 3,3-dimethyl-2 butanone
1. For each of the following structures, i. write the IUPAC name. (2 pts.) ii. classify each halogen as 1º, 2º, or 3º. (1 pt.) 2. Draw structures for the following alkyl halides. Be sure to indicate any stereochemistry as needed. (2 pts. each) a. 3,6-dibromo-3,6-dichlorononane b. 2-iodo-2-methylpentane Page 3 4. Indicate which alkyl halide you would expect to react more rapidly by an S12 mechanism. (2 pts.) Explain your answer. (2 pts.) 3. i. State which reagent you would...
Which product(s) would you expect to obtain from each of the following reactions? In each part give the mechanism (Sw1, SN2, E1 or E2) by which each product is formed. Explain your reasoning. (20 pts) 6. a. NaSH OTs DMSO b. CI NaOCH3 C. OMs NaOCH2CH3 d. ON HCECNa e. KOC(CH3).3 CI Br NaOCH2CH3 CH3CH2OHH
3. For each pair of reactions, circle which you would expect to be faster (2 pts) and indicate why in around 20 words. a) i) CH3CH2CH2OH + HCl → CH CH CH CI + H2O ii) CHCH-CH2OH + HI – CHỊCH CHI + H2O OH + HBr + H₂O HOCH ) + HBr — Br., CH3 + H2O
Which alkyl halide in each of the following reactions will react faster in an SN2 reaction with hydroxide (-OH)? Explain. Hint, some of these compounds are unreactive in SN2 reactions- be sure to think about what type of alkyl halide undergoes SN2 reactions! Bromobenzene or benzyl bromide CH3Cl or (CH3)3Cl CH3CH=CHBr or H2C=CHCH2Br
For each of the following pairs of atoms or ions, state which you expect to have the larger radius. (a) Se or Ca (b) Ca or Ca2+ (c) Ca2+ or Ar (d) F or I (e) Ar or S2-