Question

1) When required to arrest status epilepticus, the administration of diazepam or lorazepam is ideally followed by the administration of _____.

• phenobarbital or carbamazepine

• phenytoin or fosphenytoin

• valproic acid or vigabatrin

• lacosamide or ethosuximide

What is the primary mechanism of action of carbamazepine, phenytoin, and valproic acid?

• Inhibiting the release of gamma-aminobutyric acid

• Increasing the influx of Ca++ ions

• Increasing T-type calcium currents

• Delaying the inactivation of the Na+ channels

3) What is the primary mechanism of action of tiagabine in the treatment of partial seizures?

• Inactivation of Na+ ion channels to decrease high-frequency firing of neurons

• Blockade of Ca++ ion channels and decreased release of the excitatory neurotransmitter glutamate

• Blockade of the neuronal reuptake of the inhibitory transmitter GABA back into its nerve endings

• Interference with both Na + and Ca++ ion channel activity to inhibit the high-frequency firing of neurons

Answer 1

A. Starus epileptis is defined as - Single seinere for 75 min or more seizures 5 menetes without patient coming in normal stafe betwew them. theng foin I fophenytoin is ideely followed (cs after with benzodiazepine administration

2. Inhibit the release of gerne. Aminobutyric acid 3. Blockage of neuronel reuptake. of history trens metter GABA its nerve endings. back into Scanned with CamScanner