Question

HIV 1 is differentiated from HIV2 at the molecular level. How does this affect differntiation of the two forms of the virus based on the specific antibody responses?

Answer 1

Answer) HUIV 1 can be differentiated from HIV 2 on the basis of specific antibody responses such as-

• In HIV 2, interleukin -2 is produced more as compared to HIV 1.
• The humoral responses of B cells such as intra-type neutralisation appears to be less extensive in case of HIV as compared to HIV 1.
• However, the innate immunity increases extensively in HIV 2 as compared to HIV 1.
• innate immunity is increased in HIV 2 by the distinctive impact of tripartite motif protein.
• Conclusively, the immune responses in case of HIV 2 is greater than HIV 1.