can you provide the mechanisms for these ether syntheses? A H₂sen to O OH -outz CH3OH...
Question 3. Provide short syntheses for the following transformations. Mechanisms are not required, but the transformations will require more than one step. (8 marks)
Provide the reagents necessary to carry out the following conversion. OH NaBH/CH3OH 1. HOCH2CH2OH/H2SO4 2. NaBH4/CH3OH 3. H30+, A 1. HOCH2CH2OH/H2SO4 2. LIAIHa/ether 3. NaOH, H20 Оно* Onone of the above
What happens in the first step of this reaction? 0 o OCH; H + CH3OH OH The hydroxyl group of the alcohol becomes protonated The carbonyl oxygen becomes protonated The methoxy group of the ester becomes protonated The carbonyl carbon becomes protonated OH Ne Cryo H SOHO 1) PB, B2 2) H20 O OH Br H or Br OH Br Why is the following reaction not reversible? O Nao O Naci CI The reactants are more stable than the products...
1. H 1. LIAIH4 / dry ether 1. LiaiH, / dry ether 2. aqueous H2SO4 O H Bous H.SO O 2. W H₂SO4 H2SO4 OH Hoc H3C0 a = Electrophilic addition b=E2 Elimination c=Syl Nucleophilic substitution d=SN2 Nucleophilic substitution e= Electrophilic aromatic substitution f=Carbonyl nucleophilic addn g=Nucleophilic subs at carbonylacyl Xfer) h = Conjugate (nucleophilic) addn Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a -i for your answers
Use step-by-step arrow pushing mechanisms to deduce the product. 1. Mg, ether Br CF3 ,H,O+ Eto sample con mor 3. L ppng
Provide the major product(s)
of the reactions below that involve carbocation intermediates:
H+ CH3OH HCI b. H+ amate c. w H20 HBr ether
Predict the product for the following reaction sequence. Br Mg/ether H_Cro H,00 OH OH А B C D A Provide the product of the following reaction CI CH,CO Na OCH O Na
Predict the product from the following sequence: H OH H2O7 N.BH CH3OH ? heat (H20) OH OH and E) H OH OH II III (Z and E) OH H H o IV OH OAV OB. О с. IV D. III E.
provide mechanisms for the
following
H₂O+ heat ОН А в с
provide a mechanism
H E O DBU, LicI H +Eto OH
H E O DBU, LicI H +Eto OH