Freides craft Acylation - give the mechanim. to get this product R2 Bie na Brz
ence between a Friedel-Craft alkylation and Acylation. Synthesis of 4-Methoxiacetophenone For this Friedel-Craft acylation we will react Anisole with Acetic Anhydride. Write the mechanism and the structure of the final product. OCH Ald + CH3- CH- --CH, CH-Cl, anisole acetic anhydride a What will be the major product for this reaction? Explain why. b) The presence of the O-Methyl group will favor what positions for the substitution? Post Laboratory Luinld when 55 of anisole react with 0.65 g of acetic
Friedel - Craft Acylation Synthesis of 4-Methoxiacetophenone Background Information 1.- What is an electrophilic aromatic substitution? 2.- Give three examples of activating groups. Explain why they activate the ring for substitution. 3.- Give three examples of deactivating groups. Explain why they deactivate the ring for substitution. 4.- Describe the difference between a Friedel-Craft alkylation and Acylation. Synthesis of 4-Methoxiacetophenone For this Friedel-Craft acylation we will react Anisole with Acetic Anhydride. Write the mechanism and the structure of the final product....
please show work. will rate
Draw the mechanism for a Friedal-Craft Acylation using AICI3 as a catalyst n-Bu A. Draw the two molecu les you would use to combine to form this product using Friedal-Craft Acylation B. Draw the mechanism for the formation of the following molecule starting with your two products and /or molecules
Friedel Craft Acylation of Anisole 1. Write balanced equations for TWO reactions that could account for the production of HCl during your experiment. 2. The product can be purified by distillation and recrystallization as well. In your opinion what advantage are there in purifying our product by column chromatography instead of by recrystallization or by distillation? 3.Why was it necessary to use 2.2 molar equivalents of aluminum chloride?
Please give a detailed mechanim
6 of 7 ..ice of reagent(s) to perform the following transformation? 4 a. I mol of Br2 b. 2 mol of Br c. 1 mol of HBC d. 2 mol of HBO ANSWER: a 54. What is the major organic product obtained from the following series of reactions? Na H ^ ^B Hà CH,CECH Lindlar catalyst b. 2 c. 3 d. 4 ANSWER: a 55. What is the major organic product obtained from the following...
Which starting material would give the following ketone product using the Friedel-Crafts acylation. Qollow Compound A Compound B c Compound D. Compound
Friedel-Crafts Acylation of Ferrocene lab. During workup of the
product, water reacts with the excess acetic anhydride to give what
side product(s)?
#6 FRIEDEL-CRAFTS ACYLATION OF FERROCENE H3PO4 DISCUSSION 1. During workup of the product, water reacts with the excess acetic anhydride to give what side product(s)?
Which starting material would give the following ketone product using the Friedel Crafts acylation adidas όόόό Which two starting materials can be used to prepare the compound in the box? Enter two numbers, in numerical order. O Trieu
give the dominate product based on the following reaction and
conditions
1. PBry, Brz 2. H20 Product?? 3. 2 eq. NH3 PH 2.0 Culori as a Quin ОН OH Br Br - IV V NH2 Br NH2 Br NE Br Br VI VII VIII IX х of OH ОН HN ОН HEN OH HN HN HN XI XII XIII XIV XV
Give the dominate product based on the following reaction and conditions specified: 1. PBry, Brz 2. H20 OH Product?? 32@g NH3 pH 20 - II III IV ago al Glo Glo -- NH2 BA Br VI VII VIII IX х OH OH OH OH HN HUN HN HN HN XI XII XIII XIV XV XI II XIII IV XII XIV V