Question

A pharmacist dissolved a few milligrams of a new antibiotic drug into exactly 100 mL of...

A pharmacist dissolved a few milligrams of a new antibiotic drug into exactly 100 mL of distilled water and placed the solution in a refrigerator (5°C). At various time intervals, the pharmacist removed a 10-mL aliquot from the solution and measured the amount of drug contained in each aliquot. The following data were obtained:

Time (hours) Antibiotic (μg/mL)
0.5 84.5
1.0 81.2
2.0 74.5
4.0 61.0
6.0 48.0
8.0 35.0
12.0 8.7
  1. Is the decomposition of this antibiotic a first-order or a zero-order process?

  2. What is the rate of decomposition of this antibiotic?

  3. How many milligrams of antibiotics were in the original solution prepared by the pharmacist?

  4. Give the equation for the line that best fits the experimental data

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Answer #1

a) this decomposition is a zero order process as rate of reaction is a constant = k

[A(t)] = [A(0)] - k t

slope of linear fit gives rate of reaction = 6.59 micro gram ml-1hr-1

at t = 0 hr original solution had 87.665 x 100 = 8766.5 micro grams = 8.7665 milligrams of antibiotics

A = 87.665 - 6.59 t

OriginPro 8.6 32-bit -ClUsersl Gupta)Documents OriginLab185User Files UNTITLED - /Folderl/ - [Graph2] File Edit View Graph Data Analysis Gadgets Tools Format Window Help Project Explorer 〔1〕 quation y a b Weight No Weigh Residua 0.15763 Sum of UNTITLED et1 concenteration 90 Pearsons -0.99998 Adj. R-Sq 0.99996 Value Standard concenter Intercept 87.665 0.1067 ation 60 50 D 40 C 30 20 10 Slope 6.589 0.01733 NT.VS Bo Work... Nor...102KB 1/13/ Gr Graph Nor... 19KB1/13/ Te Work Nor 9KB 1/13/ To Work Hidd.. 9KB 1/13/ Bo Excel Nor 8KB 1/13/.. Gr Graph Maxi 19KB 1/13/ 10 12 time (hr) AU: ON Dark Colors& Light Grids 1-Book1jSheet1lColconcenteration1:7 :Graph21 11 Radian 916 PM 1/132019 8 O Type here to search -- 8 4 2 0 87

please rate it up thanks :)

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