Reaction Mechanism:
SN1 reaction: If tertiary carbocation formed after the leaving group leaving or alkyl migration with weak nucleophile then the reaction proceeds via an SN1 mechanism. SN1 reaction will give the racemic mixture of product.
SN2 reaction: If the nucleophile is strong and the reactant has alkyl-substitution on primary or secondary carbon then reaction proceeds via an SN2 mechanism. SN2 mechanism gives an inversed( If you take R- isomer in the reactant you will get S- isomer in the product) optically active product.
E2 reaction: If the base was very strong and the reactant has alkyl-substitution on primary or secondary carbon with alpha-hydrogen then reaction proceeds via an E2 reaction.
In the first reaction, methanol is a weak nucleophile so SN2 reaction, not a preferable reaction. So SN2 reaction will give the minor product. And the SN1 reaction will give the major product.
In the second reaction cyanide anion formed from NaCN act as a good nucleophile for an SN2 reaction. So the reaction will give the optically active cyano substituted product.
In the third reaction, LDA is a strong base which will give only E2 pathway product (alkene)
In the fourth reaction, acetate anion from (NaOCOCH3) is moderate nucleophile so it will give SN2 pathway product.
In the fifth reaction, sodium methoxide is a strong base which will give the E2 reaction product (alkene) as a major product. and methoxide anion gives some amount of SN2 pathway product also.
4. (31 pts) Provide the reaction products and indicate the type of reactions ( I, UL,...
4. (31 pts) Provide the reaction product(s), and indicate the type of reactions (S1, S2, E1 and E2) and optical activity (Yes or No) in the round rectangles, respectively. If reaction does not take place, indicate "No Reaction" in the box. Draw 1 minor product Reaction type Reaction type Draw 2 major products Is the product optically active? Reaction type Draw 1 product CH2OH Is the product optically active? NaCN acetone Br Reaction type Draw 1 product LDA secondary alkyl-bromide...
4. (31 pts) Provide the reaction product(s), and indicate the type of reactions (S1, S2, E1 and E2) and optical activity (Yes or No) in the round rectangles, respectively. If reaction does not take place, indicate "No Reaction" in the box. Draw 1 minor product Reaction type Reaction type Draw 2 major products Is the product optically active? Reaction type Draw 1 product CH2OH Is the product optically active? NaCN acetone Br Reaction type Draw 1 product LDA secondary alkyl-bromide...
4. (31 pts) Provide the reaction product(s), and indicate the type of reactions (S1, S2, E1 and E2) and optical activity (Yes or No) in the round rectangles, respectively. If reaction does not take place, indicate "No Reaction" in the box. Draw 1 minor product Reaction type Reaction type Draw 2 major products Is the product optically active? Reaction type Draw 1 product CH2OH Is the product optically active? NaCN acetone Br Reaction type Draw 1 product LDA secondary alkyl-bromide...
(31 pts) Provide the reaction product(s), and indicate the type of reactions ( S1, S2, E1 and En and antical activity (Yes or No) in the round rectangles, respectively. If reaction does not take place indicate "No Reaction in the box Draw 2 major products Reaction type Draw 1 minor product Reaction type Is the product optically active? Draw 1 product Reaction type CH,OH NaCN acetone Is the product optically active? arrier Draw 1 product Reaction type secondary alkyl-bromide LDA...
(31 pts) Provide the reaction product(s), and indicate the type of reactions ( S1, S2, E1 and En and antical activity (Yes or No) in the round rectangles, respectively. If reaction does not take place indicate "No Reaction in the box Draw 2 major products Reaction type Draw 1 minor product Reaction type Is the product optically active? Draw 1 product Reaction type CH,OH NaCN acetone Is the product optically active? arrier Draw 1 product Reaction type secondary alkyl-bromide LDA...
Draw 1 minor product Draw 2 major products Turn your answer in BEFORE the next lecture. Late submission will not be accepted. Scratch paper and scanned copy will not be accepted. Reaction type Reaction type is the major products mixture optically active? (write yes or no) Draw 1 product © © NaSCHE DMSO Q. Provide the reaction product(s), and indicate the type of reactions (SN 1, SN2, E1 and E2) in the round rectangle. If reaction does not take place,...
please help! Draw 2 major products Draw 1 minor product Turn your answer in BEFORE the next lecture. Late submission will not be accepted. Scratch paper and scanned copy will not be accepted. Reaction type Reaction type Is the major products mixture optically active? (write yes or no) Draw 1 product Hea NaSCHE DMSO Q. Provide the reaction product(s). and indicate the type of reactions (SN 1. SN 2, E1 and E2) in the round rectangle. If reaction does not...
4. Provide the products of each reaction (3pts. 2pts) 1. H30 OCH3 2. NaOCH; CHOH2 OCH 3. Ht, A 4. NaCN 1. LDA 2 Pho 3. H+, A 4 EtMg Br
2. Predict the products for the following reactions, indicate major and minor products where applicable H =CH1) NaNH, a) HC "*2) EtBr Lindlar's Cat. CH, O HBr 80°C H, CH, CH, CH, NaH HC HC - NaCN CH₂ сн, он CH3 K O-t-Bu in modo ) HEC- E100C Epoc=_cooke +ů C OOEt + -
4. Provide the products of each reaction (3pts, 2pts) 1. HO- Осн. 2. NaOCH CH,OH ? OCH 3. H.A 4. NaCN 1. LDA 2. Pho 3. H, A 4. EtMgBr