Question

Glutamic acid (shown below) has a pi of 3.2. What is the structure of glutamic acid at pH = 10? H3N H3N 02H H2CO2 CO2H لم CO2H HaN H2N Hanco 0H coo H₂N

Answer 1

Glutamtic acid Çooo H2NH CH2 CH2 cooo pH 10 pl At this pH the molecules on average have no net charge, present as zwitterionic molecule. When the pH of the solution is greater of PI (pH >pl) then amino acids show negative charge. When the pH of the solution is smaller of pI (pH <pl) then amino acids show positive charge. here, the pH of the solution is 10 which is greater than its pI (3.2)means the average net charge on serine is negative.