Question

Case 6: Gertie a 61.year-old female Subiective • Certe presents today with a history of depression which has not be typical medications • She has tried several SSRIs, SNRIs, and a Tricyclic anti-depressant ovet • Her depression has gotten significantly worse since the recent passing o * not been responsive to depressant over the years recent passing of her husband • • Patients is alert and oriented Vitals are WNL Assessment & Plan: • . 4 Atypical depression Gertie's psychiatrist is starting her on Nardil (phenelzine) 15mg tablets Initial Sig: 1 tab PO qd xl day, then 1 tab PO BID xl day, then 1 tab PO TID weeks then Early Phase Sig: 1 tab PO BID x2 weeks, then I tab PO QD x2 weeks then, Maintenance Sig:: 1 tab PO qod 36. Name three high tyramine containing foods that this patient should avoid while on this medication: 7. Which of the following emergencies can result when a patient who has been prescribed MAOI medication consumes too many high tyramine containing foods? Serotonin Syndrome b. Epilepsy c. Hypertensive Crisis d. Extrapyramidal Symptoms This interaction would be considered what type of reaction? Drug-Drug b. Food-Drug Herb-Drug

Answer 1

36 Name thru high tyoaminc Containing fnds -that this patient Should avoid while on this medi cahion; Aged Chee ( Cheddar, Camunbert) 1) Saucage) Agedmeat and fish C Baon, 2) 3) Concentrated Veast extaau Cmarmitz) High tyramine Containing foedi Should avoid by the patient ahile takina phenelzine Tyramine is noTmally broiken dovon in our bady by an enzyne mono amîno oxidate MAo nioitors ane taken, exunive amounts of tyramine enter the blood Stream, bading to te ahase o adrenaline like Substanau 31. cc) Hypertencive Crisis Foods high in tyramine are ingeuted, a hypertensive Crisie Can Tut, as tyamine Can displau Stored mono aminu Sush as dopamine norzpinephrine and epinephrine from presynaptic Visides 38 b) Food Dnug interaution