Question

ATP synthase is located in or on the X membrane. There are Y subunits that bind ADP and inorganic phosphate and change Z during the synthesis of ATP. х Z A outer mitochondrial two quaternary structure inner mitochondrial three conformation outer mitochondrial three conformation Ꭰ ] . cell four primary sequence 9 Consider the following reaction, which is analogous to ones you have encountered. CH сно CHz C-C-COO WE CH-C-" + A + B ---> 'SCOA +C+D Both substrates A and B contain a vitamin as part of their structures. Name these two vitamins. pg. 14 A B C D Study Guide for the Metabolism Section Riboflavin (=B2) and niacin Riboflavin and thiamine (=B1) Niacin and pantothenic acid Pantothenic acid and riboflavin
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Answer 1

8. ATP synthase is located on the inner mitochondrial membrane. There are three subunits that bind ADP and inorganic phosphate and change conformation during synthesis of ATP.

B) inner mitochondrial              three                     conformation

Explanation: If we observe the structure of mitochondria and ATP synthesis process we will find that ATP synthase or complex V is located in the inner mitochondrial membrane adjacent to ETC complex. It have two part F0 and F1 and F0 embeded in the membrane where F1 projecting towards inner side of mitochondrial matrix. In F1 structure there is three alternating subunits of alpha and beta which binds to ADP and inorganic phosphate and change their conformation to open tight and close during synthesis of ATP.

9. The two vitamins are

option D) Pantothenic acid and riboflavin

The biochemical reaction involve alpha keto acid which converted to alpha ketoyl CoA so for this purpose CoA is required which only obtainable from pantothenic acid or Vit B5. Along with this there must be another co-enzyme which can accept the reducing equivallents or hydrogens. Riboflavin can produce co-enzyme FAD which converted to FADH2 in this reaction.

10. PEP or phosphoenol pyruvate is a compound with high energy bond. As such it is involved in the transfer of

B) phosphoryl to ADP

Phosphoenol pyruvate formed in the glycolytic pathway by the Enolase through 2-phospho glycerate. This is a high energy compound due to phospate bond. So this compound transfer its high energetic phosphoryl group to ADP to form ATP which utilized by cell to perform various work. Remaining part of the PEP converted to pyruvate which is in terms intermediate for TCA cycle and gluconeogenesis process for further utilization as per body's requirement.