Question

Client A. G. is an 80 year old make with a diagnosis of both Parkinson's and Alzheimer's diseases.

Consider the pathopharmacological basis for creating a plan of care. (Hint: think about which medications would decrease/increase dopamine and which would decrease/increase levels of acetylcholine. How would those medications affect the underlying disease processes?) You do NOT have to consider which medications you would prescribe or at which doses - that is beyond the scope of this course, but you do have to consider how a nurse would work with an interprofessional health care team AND relate your knowledge of understanding how medications affect these disease processes.

Answer 1

1. Parkinsonism is a disorder of central nervous system that affect dopamine producing neuron cause movement disturbance and tremer.

2. Alzheimers disease is a neuro degenerative disorder in which decrese level of acetyl choline and characterised by progressive cognitive decline and dementia.

Drug decrease dopamine level:

L- tyrosin

Mucuna

Thieanine

Rhodiola

Drug decrease dopamine level:

Mono amino oxidase inhibitor

Drug increase acetyl choline level:

Bacopa

Citicholine

Gala ta mine.

Drug decrease the acetyl choline level:

Nitrates

Mucimol