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Your pediatric patient recently received a DTaP vaccination, providing immunity to diphtheria, tetanus, and pertussis. If...

Your pediatric patient recently received a DTaP vaccination, providing immunity to diphtheria, tetanus, and pertussis. If your patient is exposed to pertussis a few weeks following this vaccination, which of the results would you expect to receive when measuring the patient's antibody titers?

a) A rapid decline in the proportion of IgE antibody

b) A sharp decline in the production of IgD antibody

c) A rapid surge in the production of IgG antibody

d) A sharp increase in the proportion of IgM antibody

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Answer #1

Pertussis or whooping cough is a highly contagious respiratory tract disease and can be preventable by DTaP vaccination. It is caused by a bacteria called Bordetella pertussis. Here the situation is different. If the patient is exposed to pertussis after the vaccination, the possible result after examining the patient will be,

c)A rapid surge in the production of IgG antibody

lgG antibody is the one which is produced by the body to resist against pertussis. So there will be a rapid surge in the production of lgG antibody reflecting a primary immune response.

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