- (20pts) Predict the products and mechanisms of the following reactions. If more than one product...
Predict the products and mechanisms of the following reactions. When more than one product or mechanism is possible, explain which are most likely. (a) 1-bromohexane + sodium ethoxide in ethanol (b) 2-chlorohexane + NaOCH3 in methanol (c) 2-chloro-2-methylbutane + NaOCH CH in ethanol 23 (d) 2-chloro-2-methylbutane heated in ethanol (e) isobutyl iodide + KOH in ethanol>water (f) isobutyl chloride + AgNO3 in ethanol>water (g) 1@bromo@1@methylcyclopentane + NaOEt in ethanol (h) 1-bromo-1-methylcyclopentane heated in methanol
PROBLEM 7-33 Predict the products and mechanisms of the following reactions. When more than one product or mechanism is possible, explain which are most likely. (a) 1-bromohexane + sodium ethoxide in ethanol (b) 2-chlorohexane + NaOCH, in methanol
Predict the products of the following reactions. When more than one product is expected, predict which will be the major product. 7.38 X) do in MOCH. y) by a masay, Met z) by Hesoy, Heat Moclamado 아
umroeunene Predict the products of the following reactions. When more than one product is expected, predict which will be the major product. OH H,SO (b) H,PO heat 1,38 x) en Nauciet). Y yo hasa, tet z z Noche
4. Predict the products of the following reactions & indicate whether they are most likely to go through an SN2, SN1, E1, or E2 mechanism. NaCN DMSO NaOH CH3OH heat Only one product is formed in the following E2 elimination reaction. Draw an arrow-pushing mechanism for the reaction and provide the correct product structure. Include a 3-D drawing (chair conformation) displaying proper stereochemistry of the transition state to explain formation of only the major product. CH3 •Br NaOCH3 ~"'CHS
PROBLEM 7-24 1. Predict the elimination products of the following reactions. When two alkenes are possible, predict which one will be the major product. Explain your answers showing the degree of substitution of each double bond in the products. 2. Which of these reactions are likely to produce both elimination and substitution products? (a) 2-bromopentane + NaOCH3 (b) 3-bromo-3-methylpentane NaO (c) 2-bromo-3-ethylpentane NaOH Me (Me= methyl, CH3)
write structures for the products of the following reactions. If more than one product will be formed indicate which will be the major product. CH3 KOLBU L (CH3)3cor is t-Buo-1 : L Br . b) NaOCH CH, d) (ТОН H2SO4 heat CH,CH
Predict the substitution product(s) for each of the following reactions and mechanisms by which they are formed. If no reaction is expected, write no (a) (R)-2-bromobutane with sodium iodide in acetone (b) (R)-3-bromo-3-methylhexane with H20 (c) trans-1-bromo-2-ethylcyclopentane with potassium ethoxide in ethanol (d) trans-1-bromo-3-methylcyclopentane with Nal in acetone 5. For the following set of compounds, predict the order of reactivity with sodium iodide in acetone solution (list them in increasing order of reactivity). C. D. 2-bromobutane 1-chlorobutane 2-chloro-3-methylbutane 2-bromo-2-methylpropane 1-bromobutane...
5. Predict the major organic products of the following reactions. Show all asymmetric carbons with wedgeldash notation (i.e., as shown in the starting material). If a reaction produces a racemic mixture, show only one of the enantiomers produced. Carefully note the requested reaction mechanism for each reaction. (20 pts) NaOCH3 CH3OH SN2 Br CH3OH SN1 Br NaOCH3 CH3OH E2 Show Zaitsev product Br CH3OH Br E1
Q. Predict mechanism type (SN1, E1, SN2, E2) for the following reactions. If more than one is possible, predict which mechanism is more likely and explain why. 5 - HI ح . 0H SNI KOCH2CH3 KOCHCH - I want to wors. NaOH, H2O, 100°C في NaCN ي . HO )..NC دا SN2