(a) Answer TWO of (i), (ii) or (iii) [2 x 6 marks] (i) The two isomers...
6. Predict which of the following two isomers (cis- or trans-) will undergo an E2 elimination under the treatment with EtoNa in EtOH more rapidly. A) For the explanation of the reaction rate, draw chair conformations for each isomer, determine which conformation is more stable . B) Draw the major product and the mechanism of the reactions. CI cis-isomer trans-isomer
5. Devise a multi-step synthesis that will provide the product shown from the given starting material. (Challenging!) 6 Multiple Steps 3. When diastereomers I and I undergo an E2 elimination on treatment with sodium ethoxide in ethanol, one of the isomers react 500 times faster than the other one. Also, one isomer gives only A as a product and the other isomer gives a mixture of A and B as products. Determine the products of each isomer and explain your...
4. The following 2 isomers are reacted with HBr, first at low temperatures (<-20°C) and then again at elevated temperatures (>50°C). H,CO CHE CH, HCYCH, сн. a) Draw the most stable allylic cation that would form during the reaction for each isomer. b) Draw the reaction for each condition for each isomer (4 altogether), and provide the expected major product in each case. c) The following reaction coordinate can correspond to only the reactions of one of the isomers provided....
(5 Marks) B. Answer the questions based on the structures given below i. ii. нонс нонс OH CH HOR OH HO CHOH CH, OH CH OH HO HOM H -OH CH, OH c. Identify the compounds ii, iii and iv as D or L. Explain how you came to this conclusion (2 marks) d. Draw the Fischer projection, enantiomer and indicate which carbons are chiral or achiral for the compound ii. (3 marks) e. Among the compounds iii and iv...
For ii I got rs and Sr stereochemistry. For iii I got racemate. For Iv, I think there's 4 stereo isomers? I'm not sure. QUESTION 1 15 marks] e structures (no mechanism required) of the TWO (2) stereoisomeric oxiranes formed from the epoxidation reaction of (E)-2-butene with meta-chloroperoxybenzoic acid l mark] (i) Assign R or S stereochemistry to the stereogenic carbons in each of the oxirane products. I1 mark] chch yfat muf l mark] (iv) Indicate and explain the expected...
CONFIDENTIAL chemicals. Consider the molecule S below undergo certain reaction with the following Draw the product/s for each reaction. (b) Molecule S (i) O/H2O Answer: (2 Marks) (ii) Na/NH Answer: (2 Marks) (ii) Determine either elimination, addition or substitution reaction that obey the Markovnikov rule. Answer: CONFIDENTIAL chemicals. Consider the molecule S below undergo certain reaction with the following Draw the product/s for each reaction. (b) Molecule S (i) O/H2O Answer: (2 Marks) (ii) Na/NH Answer: (2 Marks) (ii) Determine...
I. The constitutional isomers are not distinguishable by the two dimensional structure True False II. The stereoisomers cannot be distinguished by the two dimensional structure True False III. Optical isomerism is a type of conformational isomers. True False IV. Conformers and rotamers are not the same thing. True False V. Staggered conformation of propane is more stable than eclipsed conformations True False
For part f iii) you should include a diagram for each step of the mechanism and an explanation as this is your opportunity to demonstrate your understanding. e) One of the products gives a silver mirror when warmed with Tollen's reagent. State the identity of this product and state the functional group it contains. f) 2-methylpropan-1-ol is heated with an excess of concentrated sulphuric acid (H2SO4) in order to cause an elimination reaction. i) Provide a full chemical equation...
Name: 1 What is the major product of the following reaction? (CHдЬсo (CHЊ,сон Br IV A) I B) II C) III D) IV 2. What is the major elimination product obtained from the following reaction? NaOMe MeOH Br IV A) I B) II C) III D) IV 3. Which of the following is the most reactive substrate in an E2 reaction? CHiCH(Br)CH2CHs (CHs)sCBr CH3Br CH3CH2CH2CH2Br п ш IV I B) II С) ш D) IV A) I 4 Which of...
(i) explain how they differ. b. (ii) Explain how the following reaction was used to deduce the mechanism of inner sphere electron transfer. [Co(NH,),Cl]Cr(Hd+SH,OCo(H,O)+ [Cr(HO),ci+5NH 8 marks] (i) Given the following ligands, suggest which one you would use as a chelating agent to treat an excess of Fe(III). Explain your choice. c. HS SH он HS NH2 Ci) Assuming an octahedral geometry, draw the strueture (inecluding any possible isomers) of the neutral Fe(III) complex that would be formed if it...