Question

6. Jennifer is ordered IV Cefazolin. She weighs 10kg. The safe dose of Ceraz 50-100mg/kg/day IV in equal doses 8 hourly. a. What is the lowest daily amount she can safely receive? b. What is the highest daily amount she can safely receive? C. If a safe dosage of Cefazolin is 75mg/kg/day in equal doses 8 hourly, how many mg does the patient require for each dose? d. The instructions on the vial tell you to mix the 500mg vial with 2ml sterile water to obtain a concentration of 225mg/ml. How many mis will you need to draw from the vial to administer the dose ordered in question c)? e. You need to administer the Cefazolin as an IV additive and the recommendation is to dilute it in normal saline to 5-20mg/ml and run over 30 minutes. What is the minimum volume you can dilute it to? f. What is the rate you need to set your pump if you want the medication and the 4ml normal saline flush to be infused over 30 minutes?

Answer 1

6. weight= 10Kg

Safe dose = 50-100mg/kg/day

1. Lowest daily amount she can receive = 50 × 10 = 500 mg /day
2. Highest daily amount she can receive = 100 × 10 =1000mg/day
3. Safe dose = 75mg/kg/day

Daily amount for the patient = 75 × 10 = 750mg/day

How much is given in each dose = 750/3 = 250mg

4. Dose prescribed = 250mg

Dose in hand 225 mg/ml

How much ml should be administered =

dose prescribed x amount in hand dose in hand

                                                                 = = 1.1 ml

250x 1 225