Question

1. Use numbers to indicate which compound will read the fastest by the these alcohols with Nal in acetone. With 1 being the fastest and being the sot 2 mechanismo Hgc er HOCH HC 2. Show the step by step mechanism to account for the following transformation. Also predict une major product formed. (20 points) com, HB HCX HBOX Br HACCHE Syl condition CH нус сн, он orts CH H₂C Dr. Denton

Answer 1

An SN² reaction involves, the approaching of the nucleophile to the carbon atom to which the leaving group is attached.

1. An An N² reaction involves the approching of nucle of to carbon atom to which the leaving group tea when the steric hindrance in alkyl halides increases, the reactivity tounds for reaction decreaus. (1323) Since, sterie hindrence increasing order, (given Compounds ) i. (primary alkyl holide) 2. alkyl halide s-akkigt halide (l-alkyt halide with storic hindrence) Nore. Acelone less steie hindrence ne faster 6.B ( Transition state) CH3 CH3 e Nas acelne nos lubos a steric huvtrence Encreases. She reactivity decreases. arate decease. u-alkyl halide H CH3 Nas/acetone more les deric hindrance sua reactivity Cla @ was laudages use the minerale, mis on vanlig Nas/acetone -alkyt halide with steric- hundrene, sie, with reactivity decreases [An SN² reaction goes with inversion of contigention I.

& Ans! OH. CH3 ON I Cone. Her ne (Sy) (menor) (Major) Mechanism out 3. CH₂ -HO 9 -Cabocation ) (loss stable) Baltake on a cabecdow methyl group rignation then form & Maskocation (which is more stable) (HyperConjugation) 3 cu, Corlinor product) gegen Por Cha (major proant)