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Critical Thinking Assignment 1: Osmolarity & Diffusion The Soy Sauce Challenge An osmolarity case study: Jessica Mayer, MS, and Martin Mayer, DMSc, MS, PA-C could join, he was told he needed to do what the fraternity brothers told him for an entire day. After g off. After lunch, he told the brothers he wanted to lay down. One-and-a-half hours later, John was found John is a 19-year-old male in his sophomore year of college and decided to join a fraternity. Before he oing old out to a Japanese place for lunch, the brothers collected every bottle of soy sauce off the tables and t him he had to drink all the soy sauce as fast as he could. John hated ever minute of it, but he finished them unresponsive by his brothers. They called 911 and John was rushed to the ER. At the hospital, Johns vital signs were normal aside from a heart rate of 102 beats per minute, and he also exhibited seizure-like activity. Initial lab tests showed Johns serum sodium level was 172 mEq/L. Other electrolytes were normal hypo-hy pe
5. If John is given the D5W solution from 4c., the dextrose in the solution will quickly enter cells in his body by what method of transmembrane trafficking? What will this do to the functional osmolarity of the D5w solution? (3 points) Hint: see Silverthorn for action ofⅣ soutions,
7. Which solution would be best for John to receive to restore plasma osmolarity to normal and prevent further issues? Justify your answer based on the concepts of tonicity, how the treatment will affect plasma osmolarity and water movement, and cell shape/volume changes. (5 points)
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7, When we administer D5W to any one through IV, the glucose will go in to the cell, that time the movement of solute from the extracellular fluid into the cell osmosis..The volume of cell will increase and solution will be hypotonic that time..Glucose in the cells metabolized by aerobic respiration with the end products of CO2 and water..At the end of the process D5W solution will be equal to pure water..the Tonicity of the solution is determined by comparing concentration of nonpenetrating solutes,that can not enter into the cells..If solution is less concentration and nonpenetrating solutes than the cell does,there will be net movement of water into the cell equillibrium and solution will be hypotonic..5%dextrose has zero volume of nonpenetrating solutes,so it will be hypotonic..
8. John need hyperosmotic solution of 10% dextrose..Tonicity it depends upon on the nonpenetrating solutes concentration..so solution with pure glucose will be hypotonic..when water cross the cell membrane faster than solutes the cells will be hyperosmotic, but hypotonic solution of 10% D will be at starting lose volume as water leaves but start get the volume as glucose is once transported into the cell and osmosis occur..So nonpenetrating solutes when equillibrium the cells will have gained volume..It will lower the sodium concentration in the cells ,so we can avoid further complication..

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