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Trauma and Bleeding Chief Complaint: 31 year-old Afrian American male injured whilerok-climbing History of Present Ilness: This 31-year-old male was rock-climbing with two friends at a national park 14 miles away from the nearest hospital when he suddenly lost his footing and slid 18 feet to the ground. Both friends who witnessed the fall said that he slid against sharp rock all of the way down, landing almost in a standing-up position, finally slumping to the ground. They also said that his head was not jarred during the slide. The man was alert and oriented when his friends reached him, and could move all four extremities quite easily. He had multiple scrapes over his anterior torso and a larg gash over his right anterior upper thigh (near the groin) which was bleeding profusely. makeshift tourniquet slowed the bleeding. The party was able to rad io to the park rangers station for help. The ranger, in turn, contacted the med-evac unit at the city hospital. The helicopter located and evacuated each arm in-fligh the man. A large-bore IV was placed in t, and normal saline fluid was administered intravenously. The patient became increasingly disoriented during the flight, reaching the emergency room a 40 minutes after the fall. Past Medical History: According to the mans friends, the patient was in good health prior to the accident, with no history of allergies, anemia, bleeding disorders, or diabetes mellitus. Family History: Family history was not attainable. The patients family lived in another state and could not be contacted. Physical Examination: The patient was lethargic but responsive to shouting and sternal pinch. He had multiple abrasions over his chin, neck, anterior thorax, and abdomen. A six-inch-long, half-inch deep laceration was noted in the right inguinal region, extending into the right, upper thigh. The tourniquet placed in this area was soaked with blood. Height 6 2, weight 205 lbs. Vital signs were as follows: HR 112 (supine) and 128 (sitting), BP 108/ 60 (supine) and 92 /52 (sitting), RR 32, rectal temp 99.4°F. Skin was cold and clammy, and nail beds, palms, and mucous membranes were pale. Carotid, radial, left femoral, and dorsalis pedis pulses were al weak and thready. Cranial nerves, to the extent that they could be tested, were intact bilaterally. Pupils were equal, regular, and reactive to light. External jugular venous collapse point was not visible in either the sitting or recumbent position. Heart sounds were regular, tachycardic, with no murmur, Ss or S4 sounds. Lungs were clear to percussion and auscultation. Abdominal guarding was noted, attributable to multiple lacerations; no masses were felt. Blood was drawn, typed, and crossed. A urethral catheter was placed to monitor urinary output, and another catheter was placed into the right subclavian vein and threaded into the superior vena cava to monitor central venous pressure. A cardiovascular surgeon was consulted for repair of the lacerated right femoral artery.
Laboratory Studies: Laboratory stu dies of the venous blood revealed the following: Blood Type A+ Total white blood cell (WBC) count 7,400 WBCs mm(normal = 4,000 to 1 1,000) (normal=55-70%) normal 42-54%) normal 14-18 gm / di) (normal =136-145 mEq /L) normal 3.5-5.1 mEq/L) normal 96-106 mEq/L) normal= 6-23 mg/dl) (normal 0.7-1.5 mg dl) (normal 70 160 mg / dl) (normal 0-33 IU /L) (normal 041 IU/L) Differential WBC count revealed 59% neutrophils Hematocrit = 46% Hemoglobin 15.0 gm / di Sodium (Na)- 138 mEq /L Potassium (K) 5.1 mEq/L Chloride(Cl)=104 mEq /L BUN-27 mg/d Creatinine1.9 mg/ d Glucose 165 mg/d SGPT> 411U/L SGOT48 IU/L Laboratory studies of the arterial blood revealed the following: Blood pH 7.28 pCO2 31 mm Hg po2 78 mm Hg Hemoglobin-O2 saturation-88%(normal:94-100%) HCO3]14 mEq / L normal-7.35-7.45) normal 40 mm Hg) (normal= 90-100 mmHg) (normal-22-26 mEq / L) Urinary output in first 60 minutes in ER was 20 ml (color was dark yellow). Urine specific gravity1.029 (normal 1.003-1.030). Central venous pressure ranged from 1 to 3 cm H20 throughout the cardiac cycle (normal = range = 5.5 to 13 cm H2O). ECG revealed normal sinus rhythm with slight ST-depression in most leads. As soon as whole blood became available, 2 units were rapidly transfused into this patient. Questions:
5. What is specifically causing each of the following findings? A. orthostetic hypotension B. elevated creatinine and BUN C. elevated SGOT and SGPT D disorientation and lethargy E. decreased central venous pressure. F. pale nail beds and mucous membranes G. ST-segment depression 6. How would you characterize this patients acid-base status? Give specific evidence for your answer 7. Poiseuilles equation describes the variables that determine arterial blood flow rate. How have the variables in Poiseuilles equation been altered from normal in this patient? 8. What is the hematocrit? 9. If the he 10. If this patient were stabilized, how would his hematocrit change over the next 24 matocrit was in the normal range, why was the patient given 2 units of whole blood? hours? 11. Why was whole blood (rather than packed RBCs) given to this patient? 12. Physicians attending to this patient debated ordering an abdominal CT scan, but decided ultimately against it. Why might they have ordered one?
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5.a) orthostatic hypotension is due to hypovolemic shock caused due to injury to the femoral artery which resulted in severe hemorrhage and blood loss .

b) elevated creatinine and BUN due to decreased blood supply to the kidneys as a result of blood loss .

c) elevated SGOT and SGPT due to liver injury as a result of less blood supply .

d) disorientation and lethargy is also due to decreased blood supply to the brain as a result of shock

e) decreased central venous pressure due to hypovolemic shock .

f) pale nail beds and mucous membrane due to loss of blood

g) ST segment depression as a result of ischemia

6. Patient is under acidosis as the pH is 7.28 ,HCO3 is 14 mEq and PCO2- 31mmhg and PO2 is 78mmhg .

pH and HCO3 less than the normal limits leads to metabolic acidosis

and PCO2 and PO2 more than the normal limits leads to respiratory acidosis

7. Poiseuilles formula -V = πpr​​​​2/ 8×fluid viscosity ×l

= In this case there is damage to the femoral artery which are caused change in the radius , pressure ,and fluid viscosity due to a six inch deep cut in the right femoral artery and severe hemorrhage.

8. Hematocrit is the measure of the red blood cells in the total volume of blood.

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