Question

Describe the chirality of the following amide: ОН NH 3S,4R 3R, 4R 3R,45 35,45 Enviar Respuesta Tries 0/1 Describe the chirality of the following ketone: Ph нон 3R,55 3R,5R 38,5R 35,55 Enviar Respuesta Tries 0/1

Answer 1

Accroding to the CIP rule if the lowest priority group is below the plane , then the clockwise rotation will give R configuration and the Anti-clockwise configuration will give S configuration. when the lowest priority group is above the plane , then the clockwise rotation will give S configuartion and the anti-clockwise will be R configuration. Highest priority group is denotated by 1, subsequently the lowest priority group will be denotated by 4 OH IIIIIIII NH2 Lowest priority is above the plane and rotation is clockwise so it is S I OH 3 NH2 Lowest priority is above the plane and rotation is clockwise so it is Hence the configuration will be 3S,4S

Ph. - H. Lowest priority group is above the plane and the roatation is clockwise so S A 1 Ph. Н. ОН Lowest priority group is below the plane and the rotattion is clockwise hence the configuration will be R Hence the overall configuration is 3S,5R