WIN Sodium elle 2.ethoxy-1-methylcyclopentanol. base Base-catalyzed: The nucleophil attacks the less substituted can which is less...
WIN Sodium elle 2.ethoxy-1-methylcyclopentanol. base Base-catalyzed: The nucleophil attacks the less substituted can which is less hindered. 0 0-CH.CH OHH CH, OCH,CH, CH, (H (b) Under acidic conditions of the protonated epoxide. T conditions, the alcohol attacks the more electrophilic tertiary carbon atom tonated epoxide. The product is (E)-2-ethoxy-2-methylcyclopentanol. CH, OH 0 Co+ CH, H CH,CH,-0-H H CH.CH PROBLEM 24-27 Predict the major products of the following reactions, including stereochemistry where appropriate. (a) 2,2-dimethyloxirane + H/ H (oxygen-labeled water) by 2,2-dimethyloxirane + Hlo / (c) (2S,3R)-2-ethyl-2,3-dimethyloxirane + CH3O/CH OH (d) (25,3R)-2-ethyl-2,3-dimethyloxirane + H/CH3OH