Question

Instructions: These problems can be done using only reactions learned in the chapters on substitutions and alkynes. For any row you may use acetylene, alkyl halides that have only 1 carbon, 1-bromo-2, 2-dimethylpropane and/or any other common reagents whose carbons are not going to be incorporated into the target molecule. You may also use monofunctional alkyl halides with any carbon skeleton but no more than 5C. Show how you might prepare the compounds listed for you in BB. Be sure to indicate the numbers assigned to your problem molecules. Note: all the structures in each row have something in common. Knowing what that is may help with your approach to the synthesis.

Answer 1

For the three synthesis of the given compound, I have just used the following compounds such as Monofunctional alkylhalide for the synthesis of the Compound 1(4- Bromo 2-pentanol), and also for the compound 21(3-Bromo propanal), and 1- Bromo -2,2 dimethyl propane.

Synthetic methodology for the Compounds 21, 41, 1, respectively is given as follows.
Target more anlei Synthesis :- from acetylene :- n Bul H - CEC-H H-CEC-Li +n-Butaire (is Hg 504 H-CEC-H H₂504 il Nabha acetylene H CH3 linah. acetaldehyde. to y Mezsiel s oxymerarration. Demerewration" or simea CH, silylenol ether- ÜHE و رعا mono functional alkyl halide CH Target moleanle.

y tenant molander Target molemler Synthesis: from acetylenes- H-CEC-H 2. equivalent > of nBuli Li-CEC-li acetylene requivalent Br 아 J 1-Bromo-2,2 dimethyl propane. i Hg504 Hlason n ezerd -CEC- I NABHA oxymerenration, bemerenratros! chert Target motemple

OH Also from artytene :- H -(=C-H I canivalent of B JE 4 - esc-H from the use of mono functional alkyl halide: Brt (3.5 equivalent) Meo V of Meli 4- Bromo-2-pentanol ! and me ori H30+ Hoot Target molembe.