Question

This is for the Grignard Reaction laboratory. Please help me answer this question, much appreciated.

1. If a student performing Laboratory with Grignard reaction accidently used acetone as the reaction solvent instead of diethyl ether, what would the major organic product(s) be? Draw the structure of the product(s) (no mechanism necessary).

b. What was the purpose of adding magnesium sulfate in this experiment?

c. Grignard reagents react with both aldehyde and ketone functional groups. How do you predict the reaction rate would change if the aldehyde in this lab was switched to a ketone? Explain your answer.

d. Acid chlorides (R-COOCl) are a functional group that can be synthesized from a carboxylic acid, and are very useful as “building blocks” for a wide variety of reactions. They react with Grignard reagents in a 2:1 ratio of Grignard:acid chloride. Predict the major organic product of the following reaction and show the mechanism for how it is formed

Thank you very much!

Answer 1

ra ! Rgx 0 Ongix cine CHet en 07019 na orig CH3 Xou ett ett Mgagnesium sulfate is used as dooying agento in grignard reaction. The coater produced during the reaction affects the yield and rate of the reaction thus magnesium sulphate es added to remove it 121 CH3 CH3 CH3 + Rongt Rugr Borsically what happen, the fR) group of the grignard will attach the xero group of the aldehyde/netone Now the at of fe=o) and (a) of tR)) 11. maintain the rate. Aldelade in more reactive as the x=0 group is more positively changed compared to the ketone whose positive change is reduced by all tI of (elly groups in ketone and hence rate in redneed. Rugx, e R- e- d - R éel Re - R el dong xd . . . . . . . . . Rze-ot R-CR IMGA