Question

HDN= Hemolytic disease of the newborn

2. What test would you perform in order to identify the antibody causing the HDN? 3. A new tech is investigating a suspected HDN case but the mother's cells keep on reacting as DAT negative. Assuming that HDN is actually occurring, what is the most likely error being made by the tech? 4. How would you change your titration testing procedure if you thought the antibody causing HDN was an IgG antibody against ABO? 5. During an HDN workup, a mother's titer is only 8, however the fetal cells are DAT positive and are coated in complement. What is your opinion of the fetus’ risk of HDN? Be sure to explain your answer

Answer 1

2.The direct albumin test(DAT is used to help identify the antibody which cause the HDN. HDN is hemolytic anemia. It is the most important cause of fetal loss. If the blood type and RH factor is different of baby and mother, that is the cause of HDN.