Question

Drugs can have multiple drug actions in the body. For example, the drug fluticasone propionate is a steroid that can be used topically to relieve inflammation and itching associated with skin diseases such as dermatoses and psoriasis. It can also be used intranasally or orally to manage symptoms of allergic and non-allergic rhinitis and asthma. Fluticasone propionate binds to and activates the glucocorticoid receptor and also blocks the activity of an enzyme known as cytosolic phospholipase A2. Therefore, it has multiple drug actions at multiple molecular targets in the body. Which of the following accurately describe fluticasone propionate? (Select two answers.)

a receptor antagonist

an enzyme activator

an enzyme inhibitor

a receptor agonist

Answer 1

Option C and D

An enzyme inhibitor.

A receptor agonist.

Fluticasone propionate treats nasal symptoms and it is an antihistamine.

Fluticasone propionate is an enzyme inhibitors which blocks the enzyme activity.

It is an agonist to the receptor of glucocorticoid.