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Answers 3-9. Explain work.
Heparin Worksheet Your patient has a new order for High Dose Heparin Choose the correct protocol for this patient and calcula
WEIGHT-BASED (HIGH DOSE) ADULT HEPARIN PROTOCOL For treatment of DVT and PE Heparin infusion is standardized to heparin 25,00
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Answer #1

As, per the protocol mentioned the initial dose is 80 units per kg. This patient weighs 75 kgs. So, the initial bolus dose in this patient is 80*75 = 6000 units of heparin.

3) So for the bolus dose of 6000 units of heparin 6 ml should be drawn from 1000 units/ml of heparin 10 ml vial.

1000--1 ml

6000--x

X = 6000 x1 = 1000 = 6ml

4)If the concentration is 5000/ ml, then 1.2 ml should be drawn for bolus dose of 6000 units.

5000--1 ml

6000--x

X = 6000 x 1= 5000 = 1.2ml

5)Initial infusion dose is 18 units/ kg/ hour. So, for this patient 18*75 = 1350 units/kg/hour.

6) The two values required to set the infusion pump are dose(in units) and time ( in hours).

7) By entering these two values, the third value the pump calculate is how much ml per hour to be given.

8) First PTT should be drawn after 6 hours of heparin therapy. If baseline PTT was not drawn within past 24 hours then PTT should be done STAT (immediately).

9)As, the patient's 6 hour PTT is less than 52 .The bolus dose remains the same that is 80 units / kg = 80*75=6000 units.

Infusion dose changes, have to add 4 units/kg/hour to the existing 18 units/kg/hour that means the new infusion dose is 22 units/kg/hour. So, in this patient the infusion dose is 22*75 =1650 units/ hour.

New heparin infusion rate is calculated as follows:

Heparin infusion is available in 25000 units per 500 ml bag of 0.45% NaCl. So,

25000 = 500 = 1650 = X ; X = infusion rate.

  X = 500 x 1650 - 25000 = 33mlper hour.

So, the heparin infusion rate is 33 ml per hour.

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