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Patient 3: A 71 year old female presents to the ED in sepsis. The admitting team suspects the source of the infection to urin

3. The patient has after 3 days of appropriate IV antimicrobial therapy. The team would like your assistance choosing an oral

MIC Interp E Dilution Escherichia coli ESBL MIC Dilut E Interp <=16 > 16 8/4 >16 >16 >16 >32 Drug Amikacin Ampicillin Ampicil

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Answer #1

1)Yes, antimicrobial therapy should be broadened for more microbial coverage based on 9/20 culture result.

2) Nitrofurantoin,Trimethoprim/Sulfa,Piperacillin IV microbial are generally used in first line of treatment .

3)Ampicillin/Sulbactam antibiotic that can be used for this case.

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