Question

1. Mimi has many of the classic signs and symptoms of chronic kidney disease, including edema of the lower extrem- ities, nausea and lack of appetite, fatigue, hypertension, and elevated blood urea nitrogen (BUN) and creatinine. a. BUN is the byproduct of protein metabolism and creatinine is produced during muscle activity. Look up the normal ranges for BUN and creatinine, and fill in the table below, including the units. Based on these values, would you classify Mimi's kidney disease as relatively mild or severe? Mimi's results Normal nange Blood wrea nitrogen (BUN) 208 mg/dL 7-20 mg/dL Creatinine 15mg/dL. 0.6-1.3 mg/dl. Based on these values, I would consider Mimi's kidney disease as severe. b. The graph in Figure 1 below shows the relationship between BUN and creatinine levels and glomerular filtration rate (GFR). What is the normal range for GFR? Use the graph to estimate Mimi's GFR. Does the estimate agree with your answer to Question la above? Creatinine (mg/dL) ------ Blood urea nitrogen (mg/dL) 120 100 40 20 80 60 GFR (m/min) Himur Clamalar flutn o

please answer the 2nd portiin of part b. fully with explaination. thank you.

Answer 1

Based on the estimated GFR range, stages of Chronic kidney diseases are

STAGES	GFR (mL/min)	DESCRIPTION
G1	$\geq$90	kidney damage with normal or high GFR
G2	60-89	mildly decreased GFR
G3	30-59	moderately decreased GFR
G4	29-15	severely decreased GFR
G5	15	kidney failure

Creatinine (mg/dL) ---- 120 100 80 GFR (ml/min) 60 40 200 ood urea nitrogen (mg/dL) - GER Mimi's

The normal range of GFR is 90-120 mL/min

As per the graph, Mimi s estimated GFR ranges between 0-20 mL/min and we can observe that it would be below 15. Thus it can be concluded that she has end stage kidney failure.