2. Draw a mechanism for the following SN2 reaction? [3] Br Cos SH NaSH + NaBr...
1. Draw the transition state for the following SN2 reactions Br SH NaSH a. NaOH b. Br OH OH NaOH C. d. 2. Draw the concerted mechanism of the SN2 reactions from the previous question. a. b. C. d.
describe each as Sn1, Sn2, E1 and E2 then draw a curved arrow mechanism for each reaction. NaSH DMSO SH KOH HO DMSO Br NANH NH3 OTs NH TsO TsO CHs CH3 Nal CH3 acetone CH O O
4. Consider the substitution reaction below. (4 pts.) NaSH DMF Br SH this reaction proceeds through an Snl mechanism and not an SN2 mechanism a) Explain why this reaction proceeds through an b) Explain why this reaction produces a racemic mixture of products
Given this reaction: Br SH ☺ - Did this substitution occur via SN1 or SN2 mechanism? SN1 SN2
3. Draw the products of the following Sn1 reaction: H₃C Br + CH3OH-02 tot (R)-3-Bromo-3-methylhexane 4. Draw the products and the mechanism for the following SN2 reaction: Br + Wollonica Na SH O WS
CHE241/240 Assignment 2: SN2 and SN1 Name:Alexo.adio Hesker 1. Indicate whether the following substitution reactions will proceed by Sy or Sy? [3] Racemic NaCN DMSO 2. Draw a mechanism for the following Sy reaction? [3] SH + NaSH NASH - - NaBr + NaBt 3. Draw the transition state for the following Sy2 reaction? [3] 1. Indicate whether the following substitution reactions will proceed by SNP or Sn"? [3] MOH problemi CXCHANS H.0 NaCN DMSO 2. Draw a mechanism for...
2 Ws 1. For each of the following SN2 reactions, (i) draw the chemical reaction (reactants and products) (ii) show the proper mechanism (iii) draw the transition states a. (S)-2-chlorobutane and NaSH b. (R)-3-iodohexane and NaOH c. (R)-2-bromohexane and NaCN d. 1-bromocycloheptane and NaOH e. Ethyl iodide and sodium actate (CH:CO2Na) Br NaOH Na o NaOH Br NaCN DMF ONA 1,2-dibromoethane Nao
Numbe: Name: 25) Provide a arrow mechanis curved arrow mechanism for the following reaction ( Br NaSH SH 26) For the following reaction, label the nucleophile, electrophile, and leaving group 3 Points). Br iv
3. Write mechanism for the following reaction and draw the possible structures for C and D. NaBr/H,SO + + C + D Br Br
Predict the most likely reaction mechanism (SN1, SN2, E1, E2) and draw all products. Nato=CH₂ E2 ran Br major 2. Draw complete mechanism with arrows for the SN1/E1 mechanism. Check for carbocation rearrangements. CH3 SMI 애 + H₂O7