Question

Please answer and explain reasoning and methodology to achieve the answer.

1. (8 pts) Provide the organic products: B(OH)2 I Br Pd(PPh34 (5 mol %) dioxane/H20 K2CO3 1 equiv. 1 equiv. -N PdCl2(PPh3)2 (cat.) T + L BF3K Br IZ THF-H20 КОАс

Answer 1

CC 2 pecpph3/4 SY13 dioxenel H₂O K2CO3 The above grecction is Mechanism suzuki coupling it is a selective reaction coupling of organo boranes pdcPPh3), anyl helides and VO) Bromine is More reactive pod cpph3), +2 pphs than chlorine ET BY produk Reductive elimination oxidative Addition (pphz), pd 1 to H2o ply po len poosmetilation Tronsmetallatim - (PPhpa Red Romans indicates BCOH T oxidation state of pd The reactivity of halogas Aryl Bromide > Argleholmide The roin steps are oxidatire dadition redetive antion, Toont metallation elimination, Trana

iAC pacz (pphaly - + 2 83k - | THE H2O Konc - ar sozuki ove reaction Mechanism ~ The Above Jecation : coupling reaction. The coupling a between reaction aryl balides and organo boranes in presence of pa Catalyst pdela (pph?? lack por (pphz), instureagent 2- oxidative addition Product Reductive climaction pphz pd pphy A ^ grans metallictim ransmetallation a la themp Apr One EBEK ARAGO